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Onderzoeker
Francis Santens
- Disciplines:Biofysica, Moleculaire en celbiologie, Medische biochemie en metabolisme, Laboratoriumgeneeskunde, Microbiologie, Systeembiologie, Plantenbiologie, Biochemie en metabolisme, Medicinale en biomoleculaire chemie
Affiliaties
- Vakgroep Biochemie en Microbiologie (Departement)
Lid
Vanaf1 jan 2011 → 31 jul 2019 - Vakgroep Biomedische Moleculaire Biologie (Departement)
Lid
Vanaf15 okt 2010 → 30 apr 2017
Projecten
1 - 1 of 1
- beurs Francis Santens: Biofarmaceutische eiwitten: glyco-engineeringtechnologie voor de productie van verbeterde, homogene glycovormen.Vanaf1 okt 2010 → 5 jan 2016Financiering: IWT persoonsgebonden financ. - specialisatiebeurzen
Publicaties
1 - 7 van 7
- GlycoVHH : optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery(2023)
Auteurs: Loes van Schie, Wander Van Breedam, Charlotte Roels, Martin Frank, Ahmadreza Mehdipour, Bram Laukens, Wim Nerinckx, Francis Santens, Simon Devos, Iebe Rossey, et al.
- GlyConnect-Ugi : site-selective, multi-component glycoprotein conjugations through GlycoDelete expressed glycans(2022)
Auteurs: Karel Thooft, Wander Van Breedam, Francis Santens, Sandrine Vanmarcke, Simon Devos, Annemieke Madder
Pagina's: 464 - 471 - Engineering of protein production systems to drastically reduce glycan heterogeneity of biopharmaceuticals(2015)
Auteurs: Francis Santens
- GlycoDelete engineering of mammalian cells simplifies N-glycosylation of recombinant proteins(2014)
Auteurs: Leander Meuris, Francis Santens, Greg Elson, Nele Festjens, Morgane Boone, Anaëlle Dos Santos, Simon Devos, François Rousseau, Evelyn Plets, Erica Houthuys, et al.
Pagina's: 485 - 489 - Using GlycoDelete to produce proteins lacking plant-specific N-glycan modification in seeds (vol 33, pg 1135, 2019)
Auteurs: Robin Piron, Francis Santens, ANNELIES DE PAEPE
Pagina's: 503 - 503 - Improved sample preparation for CE-LIF analysis of plant N-glycans
Auteurs: Bieke Nagels, Francis Santens, Koen Weterings
Pagina's: 3482 - 3490 - Using GlycoDelete to produce proteins lacking plant-specific N-glycan modification in seeds
Auteurs: Robin Piron, Francis Santens, Annelies De Paepe
Pagina's: 1135 - 1137
Patenten
1 - 7 van 7
- Cells producing Fc containing molecules having altered glycosylation patterns and methods and use thereof (Inventor)
- Cells producing glycoproteins having altered N- and O-glycosylation patterns and methods and use (Inventor)
- Means and methods for the production of glycoproteins comprising homogeneous galactosylated carbohydrates (Inventor)
- Genetically engineered eukaryotic cells producing sialylated glycoproteins (Inventor)
- Means and methods for the production of glycoproteins comprising homogeneous galactosylated carbohydrates (Inventor)
- Genetically engineered eukaryotic cells producing sialylated glycoproteins (Inventor)
- Cells producing Fc containing molecules having altered glycosylation patterns and methods and use thereof (Inventor)