Onderzoeker
Séan Mc Cafferty
- Disciplines:Levensmiddelenwetenschappen en (bio)technologie, Andere chemie, Andere landbouwwetenschappen, diergeneeskunde en levensmiddelenwetenschappen, Moleculaire en celbiologie, Systeembiologie, Voeding en dieetkunde, Dierkundige biologie, Diergeneeskunde, Andere veterinaire wetenschappen, Productie van landbouwdieren, Genetica
Affiliaties
- Vakgroep Veterinaire en Biowetenschappen (Departement)
Lid
Vanaf9 jan 2015 → 24 sep 2023
Projecten
1 - 2 of 2
- Een mRNA replicon gebaseerde immunotherapeutische combinatiebehandeling
voor triple negatieve borstkankerVanaf1 jan 2016 → 31 dec 2019Financiering: FWO Strategische Onderzoeksbeurs
- OVDS Sean Mc Cafferty: Drug-controllable protein expression form IL-12 encoding modified mRNA.Vanaf1 jan 2016 → 31 dec 2016Financiering: FWO Humanitair onderzoeksproject Kom op tegen kanker
Publicaties
1 - 10 van 14
- A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity(2022)
Auteurs: Séan Mc Cafferty, A. K. M. Ashiqul Haque, Aster Vandierendonck, Brian Weidensee, Magalie Plovyt, Magdalena Stuchlikova, Nathalie François, Sophie Valembois, Leo Heyndrickx, Johan Michiels, et al.
Pagina's: 2968 - 2983 - Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs(2021)
Auteurs: Séan Mc Cafferty, Lisa Opsomer, Haixiu Wang, Hanne Huysmans, Joyca De Temmerman, Stefan Lienenklaus, Francis Combes, Niek Sanders
Pagina's: 1370 - 1381 - In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation(2021)
Auteurs: Séan Mc Cafferty, Joyca De Temmerman, Tasuku Kitada, Jacob R. Becraft, Ron Weiss, Darrell J. Irvine, Mathias Devreese, Francis Combes, Niek Sanders
Pagina's: 1164 - 1173 - Expression kinetics and innate immune response after electroporation and LNP-mediated delivery of a self-amplifying mRNA in the skin(2019)
Auteurs: Hanne Huysmans, Joyca De Temmerman, Barbara L Mui, Ying K Tam, Séan Mc Cafferty, Arlieke Gitsels, Niek Sanders
Pagina's: 867 - 878 - Bovine embryo-secreted microRNA-30c is a potential non-invasive biomarker for hampered preimplantation developmental competence(2019)
Auteurs: Xiaoyuan Lin, Evy Beckers, Séan Mc Cafferty, Yannick Gansemans, Katarzyna Joanna Szymańska-Vandendriessche, Krishna Pavani, João Portela Catani, Filip Van Nieuwerburgh, Dieter Deforce, Petra De Sutter, et al.
- Improving the repeatability and efficacy of intradermal electroporated self-replicating mRNA(2019)
Auteurs: Hanne Huysmans, Joyca De Temmerman, Séan Mc Cafferty, Francis Combes, Niek Sanders
Pagina's: 388 - 395 - Immunogenicity and protection efficacy of a naked self-replicating mRNA-based Zika virus vaccine(2019)
Auteurs: Zifu Zhong, João Paulo Portela Catani, Séan Mc Cafferty, Liesbeth Couck, Wim Van Den Broeck, Nina Gorlé, Roosmarijn Vandenbroucke, Bert Devriendt, Sebastian Ulbert, Lieselotte Cnops, et al.
- Mononuclear but not polymorphonuclear phagocyte depletion increases circulation times and improves mammary tumor-homing efficiency of donor bone marrow-derived monocytes(2019)
Auteurs: Francis Combes, Alexandros Marios Sofias, Séan Mc Cafferty, Hanne Huysmans, Joyca De Temmerman, Sjoerd Hak, Evelyne Meyer, Niek Sanders
- mRNA therapeutics deliver a hopeful message(2018)
Auteurs: Séan Mc Cafferty, Francis Combes, Hanne Huysmans, Joyca De Temmerman, Arlieke Gitsels, Niek Sanders
Pagina's: 16 - 39 - Off-target and tumor-specific accumulation of monocytes, macrophages and myeloid-derived suppressor cells after systemic injection(2018)
Auteurs: Francis Combes, Séan Mc Cafferty, Niek Sanders
Pagina's: 848 - 856