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'NOTCHing up' the in vitro production of dendritic cells
Tijdschriftbijdrage - Tijdschrift Editorial
Two studies show that adding NOTCH ligands to Flt3L cultures increases the yield of cDC1s from mouse and human progenitors. Moreover, these NOTCH-DCs more closely resemble in vivo DCs transcriptionally and functionally. This will be extremely valuable for studying DCs in vitro and for further developing autologous DC-based antitumor vaccinations.
Tijdschrift: TRENDS IN IMMUNOLOGY
ISSN: 1471-4981
Issue: 10
Volume: 39
Pagina's: 765 - 767
Jaar van publicatie:2018
Toegankelijkheid:Closed