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Onderzoeker

Angela Privat Maldonado

  • Onderzoeksexpertise:Application of low-temperature plasmas for cancer research using 3-dimensional in vitro models and in ovo TUM-CAM model Study of the effect of plasma-generated reactive species in the tumor microenvironment, pancreatic cancer cells and stellate cells, with specific emphasis on the role of stellate cells in the migration of cancer cells upon treatment Live imaging of 3D spheroids, assessment of viability, cell death. Analysis of proliferative markers, extracellular matrix components, hypoxia by immunohistochemistry / immunofluorescence Multi-arrays for 3~D spheroids in paraffin, cryosectioning
  • Trefwoorden:LEVENDECEL-BEELDVORMING, IMMUNOHISTOCHEMIE, KANKERONDERZOEK, ANTIKANKER MIDDELEN, MICROSCOPIE (FLUORESCENTIE-), IN VITRO CULTUUR, 3D SPHEROID MODEL, CHICKEN CHORIOALLANTOIC MEMBRANE MODEL, ATMOSFERISCH PLASMA, Scheikunde
  • Disciplines:Fysica van (fusie)plasma's en elektrische ladingen, Bacteriologie, Celmigratie, Cellulaire signaaltransmissie, Cellulaire interacties en extracellulaire matrix
  • Onderzoekstechnieken:• Cell culture • Light & fluorescence microscopy • 3D in vitro tumor models • Evaluation of vaccine candidates in vitro • IHC/IF, tissue processing • Method development • In ovo TUM-CAM model • Microbiological techniques
  • Gebruikers van onderzoeksexpertise:Any group willing to work with 3D spheroids in vitro, TUM-CAM model for angiogenesis and cancer research, use of low-temperature plasmas for biomedical purposes