Intracochlear Pressure Measurements to Study Bone Conduction Transmission: State-of-theart and Proof of Concept of the Experimental Procedure

© 2018 Author(s). The cochlea is the main contributor in bone conduction perception. Measurements of differential pressure in the cochlea give a good estimation of the cochlear input provided by bone conduction stimulation. Recent studies have proven the feasibility of intracochlear pressure measurements in chinchillas and in human temporal bones to study bone conduction. However, similar measurements in fresh-frozen whole human cadaveric heads could give a more realistic representation of the five different transmission pathways of bone conduction to the cochlea compared to human temporal bones. The aim of our study is to develop and validate a framework for intracochlear pressure measurements to evaluate different aspects of bone conduction in whole human cadaveric heads. A proof of concept describing our experimental setup is provided together with the procedure. Additionally, we also present a method to fix the stapes footplate in order to simulate otosclerosis in human temporal bones. The effectiveness of this method is verified by some preliminary results.

ISBN:9780735416703

Jaar van publicatie:2018

BOF-keylabel:ja

IOF-keylabel:ja

Authors from:Private, Higher Education

Toegankelijkheid:Open