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Safety of a thickened extensive casein hydrolysate formula

Tijdschriftbijdrage - Tijdschriftartikel

OBJECTIVES: Cow's milk allergy (CMA) is treated in formula-fed infants with an extensive protein hydrolysate. This study aimed to evaluate the nutritional safety of a non-thickened and thickened extensively casein hydrolyzed protein formula (NT- and T-eCHF) in infants with CMA.

METHODS: Infants younger than 6 mo old with a positive cow milk challenge test, positive IgE, or skin prick test for cow milk were selected. Weight and length were followed during the 6 mo intervention with the NT-eCHF and T-eCHF.

RESULTS: A challenge was performed in 50/71 infants with suspected CMA and was positive in 34/50. All children with confirmed CMA tolerated the eCHF. The T-eCHF leads to a significant improvement of the stool consistency in the whole population and in the subpopulation of infants with proven CMA. Height and weight evolution was satisfactory throughout the 6 mo study.

CONCLUSIONS: The eCHF fulfills the criteria of a hypoallergenic formula and the NT- and T-eCHF reduced CMA symptoms. Growth was within normal range.

Tijdschrift: Nutrition
ISSN: 0899-9007
Issue: 2
Volume: 32
Pagina's: 206-212
Jaar van publicatie:2016
Trefwoorden:(Extensive) hydrolysate, Antiregurgitation formula, Cow's milk allergy, Infant nutrition, Thickened formula
CSS-citation score:1
Auteurs:International