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Exaggerated postural blood pressure rise is related to a favorable outcome in patients with acute ischemic stroke

Tijdschriftbijdrage - Tijdschriftartikel

Background and Purpose--The effects of early upright positioning in the acute phase of ischemic stroke on both blood pressure and functional outcome have not been previously examined.


Methods--Prospective investigation of mean arterial pressure, heart rate, and peripheral oxygen saturation in the supine, sitting, and (if achievable) active standing position 1, 2, and 3 days after an acute stroke was performed. Also investigated was the presence of a significant postural blood pressure rise and fall using orthostatic definitions and the relation to functional outcome after 3 months.


Results--One hundred sixty-seven patients were included (mean age, 68.5±15.2 years; median National Institutes of Health Stroke Scale, 7). Approximately 60% of the patients were able to stand. On average the mean arterial pressure increased when patients moved from the supine to sitting (Day 1: ? 3.9 mm Hg; P

Conclusions--We found that a significant blood pressure rise during early upright positioning in patients with acute stroke was independently associated with a favorable outcome. No contraindication to early mobilization was found in this study.
Tijdschrift: Stroke
ISSN: 0039-2499
Issue: 1
Volume: 43
Pagina's: 92-96
Trefwoorden:acute stroke, blood pressure, early mobilization, outcome, stroke unit
  • Scopus Id: 84855340934