Dual targeting of tafi and pai-1

Disclosed herein is a bispecific inhibitor for use in treating thrombotic disorders, such as acute thrombotic disorders like stroke and thromboembolism. The bispecific inhibitor is based on monoclonal antibodies targeting TAFI and PAI-1, and shows efficacy in the presence or the absence of plasminogen activators such as tissue-type plasminogen activator (tPA).

Octrooi-publicatienummer: EP3102610

Jaar aanvraag: 2020

Jaar toekenning: 2020

Jaar van publicatie: 2020

Status: Toegewezen

Technologiedomeinen: Biotechnologie

Gevalideerd voor IOF-sleutel: Ja

Toegewezen aan: Associatie KULeuven