Onderzoeker
Diether Lambrechts
- Disciplines (Flanders Institute for Biotechnology):Analyse van next-generation sequence data, Celdood, Kankerbiologie
- Disciplines (KU Leuven):Morfologische wetenschappen, Oncologie
- Zie ook: Diether Lambrechts (KU Leuven)
Affiliaties
- Laboratorium voor Translationele Genetica (VIB-KU Leuven) (Afdeling)
Verantwoordelijke
Vanaf1 jan 2017 → Heden - VIB-KU Leuven Center for Cancer Biology (Onderzoekscentrum)
Verantwoordelijke
Vanaf1 jan 2017 → Heden - Lambrechts Lab (Onderzoeksgroep)
Verantwoordelijke
Vanaf1 jan 2017 → Heden - Laboratorium voor Translationele Genetica (VIB-KU Leuven) (Afdeling)
Lid
Vanaf1 jan 2012 → Heden - Centrum voor Moleculaire en Vasculaire Biologie (Afdeling)
Lid
Vanaf1 okt 2003 → 30 sep 2005 - Departement Cellulaire en Moleculaire Geneeskunde (Departement)
Lid
Vanaf1 okt 1999 → 30 sep 2003
Projecten
1 - 7 of 7
- EXPANDing Immune Cells and their Tumor Antigens during checkpoint immunotherapyVanaf1 jan 2023 → HedenFinanciering: HORIZON.1.1 - European Research Council (ERC)
- VIB Grant for Lambrechts Lab_Period:2022-01-01-2026-12-31Vanaf1 jan 2022 → HedenFinanciering: VOI - Projectmatig onderzoek
- CIRCULATING TUMOR DNA AS AN EPIGENETIC BIOMARKER FOR TUMOR RESPONSE’ — ‘INITIATOR’ - ERC POCVanaf1 aug 2020 → 31 jan 2022Financiering: HORIZON.1.1 - European Research Council (ERC)
- RESISTANCE UNDER COMBINATORIAL TREATMENT IN ER+ AND ER- BREAST CANCER.’ — ‘RESCUER’Vanaf1 jan 2020 → HedenFinanciering: Andere Eu-programma's en intiatieven
- 'Advancing a Precision Medicine Paradigm in metastatic Colorectal Cancer: Systems based patient stratification solutions’ — ‘COLOSSUS’Vanaf1 jan 2018 → 31 dec 2022Financiering: Andere Eu-programma's en intiatieven
- Exploiting GLIOblastoma intractability to address European research TRAINing needs in translational brain tumour research, cancer systems medicine and integrative multi-omics (GLIOTRAIN) - Marie Sklodowska-Curie actions (ITN)Vanaf1 sep 2017 → 31 aug 2021Financiering: HORIZON.1.2 - Marie Skłodowska-Curie-acties (MSCA)
- VIB Grant for Lambrechts Lab_Period:2017-01-01-2021-12-31Vanaf1 jan 2017 → 31 dec 2021Financiering: VOI - Projectmatig onderzoek
Publicaties
1 - 10 van 230
- Heterozygous mutations in the C-terminal domain of COPA underlie a complex autoinflammatory syndrome.(2024)
Auteurs: Bram Boeckx, Sebastian Munck, Diether Lambrechts
Pagina's: e-pub - Comparison of the single-cell and single-nucleus hepatic myeloid landscape within decompensated cirrhosis patients.(2024)
Auteurs: Dora Bihary, Bram Boeckx, Diether Lambrechts
Pagina's: 1346520 - A phase II, multicenter, open-label study of abemaciclib and letrozole in patients with estrogen receptor-positive rare ovarian cancer: ALEPRO trial.(2024)
Auteurs: Diether Lambrechts
Pagina's: 627-630 - Immune checkpoint biology in health & disease: Immune checkpoint biology and autoimmunity in cancer patients.(2024)
Auteurs: Pierre Van Mol, Elena Donders, Diether Lambrechts
Pagina's: 181-206 - A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma.(2024)
Auteurs: Joanna Pozniak, Dennis Pedri, Ewout Landeloos, Ada Nowosad, Niccolo Roda, Carlos Ariel Pulido Vicuna, Lotte Pollaris, Ruth Seurinck, Benjamin Rombaut, Frank Vernaillen, et al.
Pagina's: 166-183.e25 - Transcriptomic characterization of the histopathological growth patterns in breast cancer liver metastases.(2024)
Auteurs: Bram Boeckx, Diether Lambrechts
Pagina's: e-pub - CD4+ T cell activation distinguishes response to antiPD-L1+anti-CTLA4 therapy from anti-PD-L1 monotherapy(2024)
Auteurs: Amelie Franken, Aurelie Mechels, Orian Bricard, Jieyi Xiong, Bram Boeckx, Diether Lambrechts
Pagina's: 541-558.e7 - Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer.(2024)
Auteurs: Diether Lambrechts, Jieyi Xiong
Pagina's: 105003 - Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study.(2024)
Auteurs: Sam Vanmassenhove, Bram Boeckx, Pierre Van Mol, Diether Lambrechts
Pagina's: e247-e260 - Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders.(2024)
Auteurs: Diether Lambrechts
Pagina's: e-pub
Patenten
1 - 10 van 10
- DISEASE DETECTION IN LIQUID BIOPSIES (Inventor)
- BIOMARKERS PREDICTING RESPONSE OF BREAST CANCER TO IMMUNOTHERAPY (Inventor)
- DISEASE DETECTION IN LIQUID BIOPSIES (Inventor)
- PREDICTING CHRONIC ALLOGRAFT INJURY THROUGH AGE-RELATED DNA METHYLATION (Inventor)
- PREDICTING CHRONIC ALLOGRAFT INJURY THROUGH AGE-RELATED DNA METHYLATION (Inventor)
- RETROTRANSPOSON BIOMARKERS (Inventor)
- RETROTRANSPOSON BIOMARKERS (Inventor)
- DISEASE DETECTION IN LIQUID BIOPSIES (Inventor)
- DETECTION OF OVARIAN CANCER IN LIQUID BIOPSIES (Inventor)
- PREDICTING CHRONIC ALLOGRAFT INJURY THROUGH AGE-RELATED DNA METHYLATION (Inventor)