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Recognition Of Serious Infections in the Elderly (ROSIE)

Boek - Dissertatie

This research project focuses on the accuracy and added value of new diagnostic tools for ambulatory care, in particular for diagnosing rare but serious infections in elderly (≥65 years). Early recognition and consequent management can improve the patient's prognosis. Currently there are no validated clinical prediction rules to exclude serious infections in older adults. New point-of-care tests such as CRP, lactate or procalcitonin, could strengthen the diagnostic assessment. The aim of the PhD project is to develop a clinical prediction rule, which can be used in ambulatory care, combining clinical features and technological tests. The project will start with a systematic review of all available evidence on clinical features and blood/urine tests. Based on the findings of the review, a selection of features and tests will be included in a large prospective study. A clinical prediction rule will be developed and internally validated using multivariate analyses techniques.
Jaar van publicatie:2022
Toegankelijkheid:Closed