Onderzoeker
Alex Crawford
- Disciplines:Ontdekking en evaluatie van biomarkers, Ontdekking en evaluatie van geneesmiddelen, Medicinale producten, Farmaceutica, Farmacognosie en fytochemie, Farmacologie, Farmacotherapie, Toxicologie en toxinologie, Andere farmaceutische wetenschappen
Affiliaties
- Moleculaire Bio-ontdekking (Afdeling)
Lid
Vanaf1 apr 2013 → 30 sep 2016
Publicaties
1 - 10 van 21
- The marine biodiscovery pipeline and ocean medicines of tomorrow(2016)
Auteurs: Alex Crawford
Pagina's: 151 - 158 - Cross-species pharmacological characterization of the allylglycine seizure model in mice and larval zebrafish(2015)
Auteurs: Peter de Witte, Alex Crawford, Camila Esguerra
Pagina's: 53 - 63 - ZEBRAFISH-BASED IDENTIFICATION OF APICULAREN A AS AN ANTICONVULSANT COMPOUND FROM MYXOBACTERIA(2015)
Auteurs: Daniëlle Copmans, J Herrmann, Annelii Ny, Yifan Zhang, G Adriaenssens, R Mueller, Peter de Witte, Alex Crawford
Pagina's: 44 - 44 - MODELING OF FEVER-ASSOCIATED EPILEPSY SYNDROMES CAUSED BY MUTATIONS IN STX1B IN ZEBRAFISH(2015)
Auteurs: Aleksandra Siekierska, J Schubert, M Langlois, P May, C Huneau, F Becker, H Muhle, Arvid Suls, JR Lemke, CGF De Kovel, et al.
Pagina's: 220 - 220 - DE NOVO LOSS-OF-FUNCTION MUTATIONS IN CHD2 CAUSE A FEVER-SENSITIVE MYOCLONIC EPILEPTIC ENCEPHALOPATHY SHARING FEATURES WITH DRAVET SYNDROME(2014)
Auteurs: A Suls, JJ Jaehn, Angela Kecskés, Y Weber, S Weckhuysen, DC Craiu, Aleksandra Siekierska, T Djemie, Tatiana Afrikanova, P Gormley, et al.
Pagina's: 79 - 80 - Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes(2014)
Auteurs: Aleksandra Siekierska, Angela Kecskés, Peter de Witte, Alex Crawford, Camila Esguerra
Pagina's: 1327 - 1332 - De Novo Loss-of-Function Mutations in CHD2 Cause a Fever-Sensitive Myoclonic Epileptic Encephalopathy Sharing Features with Dravet Syndrome(2013)
Auteurs: Angela Kecskés, Aleksandra Siekierska, Tatiana Afrikanova, Alex Crawford, Peter de Witte, Camila Esguerra
Pagina's: 967 - 975 - Integration of Microfractionation, qNMR and Zebrafish Screening for the In Vivo Bioassay-Guided Isolation and Quantitative Bioactivity Analysis of Natural Products(2013)
Auteurs: Sebastian Munck, Camila Esguerra, Peter de Witte, Alex Crawford
- Validation of the Zebrafish Pentylenetetrazol Seizure Model: Locomotor versus Electrographic Responses to Antiepileptic Drugs(2013)
Auteurs: Tatiana Afrikanova, Olivia Erin Buenafe, Peter de Witte, Alex Crawford, Camila Esguerra
- Optimization and Pharmacological Validation of a Leukocyte Migration Assay in Zebrafish Larvae for the Rapid In Vivo Bioactivity Analysis of Anti-Inflammatory Secondary Metabolites(2013)
Auteurs: Camila Esguerra, Peter de Witte, Alex Crawford
Patenten
1 - 7 van 7
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy with plinabulin or halimide or diketopiperazine derivatives (Inventor)
- Treatment of epilepsy with plinabulin or halimide or diketopiperazine derivatives (Inventor)
- Treatment of epilepsy (Inventor)
- Anticonvulsant activity of bisabolene sesquiterpenoids isolated from turmeric oil (Inventor)
- Anticonvulsant activity of turmeric oil and bisabolene sesquiterpenoids (Inventor)
- ANTICONVULSANT ACTIVITY OF GSK-3BETA INHIBITORS (Inventor)