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Onderzoeker
Inge Govaerts
- Disciplines (Flanders Institute for Biotechnology):Analyse van next-generation sequence data, Celdood, Kankerbiologie
- Disciplines (KU Leuven):Systeembiologie
- Zie ook: Inge Govaerts (Vlaams Instituut voor Biotechnologie)
Affiliaties
- Cools Lab (Onderzoeksgroep)
Lid
Vanaf1 jan 2017 → 31 dec 2021 - Laboratorium voor Moleculaire Biologie van Leukemie (VIB-KU Leuven) (Afdeling)
Lid
Vanaf1 aug 2016 → Heden
Projecten
1 - 1 of 1
- De oncogene JAK-STAT signaalweg in T-cel acute lymfatische leukemie en de link met epigenetische veranderingen en RNA metabolismeVanaf1 aug 2016 → 21 dec 2023Financiering: FWO mandaten
Publicaties
1 - 6 van 6
- Identification of novel targets for treatment in T-cell acute lymphoblastic leukemia(2023)
Auteurs: Inge Govaerts, Jan Cools
- PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia(2021)
Auteurs: Inge Govaerts, Charlien Vandersmissen, David Nittner, Johan Maertens, Nancy Boeckx, Kim De Keersmaecker, Heidi Segers, Jan Cools
- Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia(2021)
Auteurs: Sofie Demeyer, Inge Govaerts, Jolien De Bie, Lucienne Michaux, Johan Maertens, Anne Uyttebroeck, Kim De Keersmaecker, Nancy Boeckx, Heidi Segers, Jan Cools
Pagina's: 801 - 811 - JAK/STAT Pathway Mutations in T-ALL, Including the STAT5B N642H Mutation, are Sensitive to JAK1/JAK3 Inhibitors(2019)
Auteurs: Inge Govaerts, Jan Cools
- Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia (vol 32, pg 788, 2018)(2018)
Auteurs: Sandrine Degryse, CE de Bock, S Demeyer, Inge Govaerts, Simon Bornschein, Delphine Verbeke, K Jacobs, S Binos, DA Skerrett-Byrne, HC Murray, et al.
Pagina's: 2731 - 2731 - Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia(2018)
Auteurs: Sandrine Degryse, Charles De Bock, Sofie Demeyer, Inge Govaerts, Simon Bornschein, Delphine Verbeke, Jan Cools
Pagina's: 788 - 800