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Onderzoeker
Jan Balzarini
- Disciplines:Microbiologie, Systeembiologie, Laboratoriumgeneeskunde
Affiliaties
- Laboratorium Virologie en Chemotherapie (Rega Instituut) (Afdeling)
Lid
Vanaf1 okt 1999 → 30 sep 2016
Projecten
1 - 6 of 6
- Exploratie van suiker-bindende stoffen en (co)receptor inhibitoren gericht tegen HIV.Vanaf1 jan 2012 → 31 dec 2017Financiering: FWO Onderzoeksproject (incl. WEAVE projecten)
- Onderzoek naar de rol van de HIV enveloppe glycanen in de virale infectie en de antivrale activiteit van suiker-bindende moleculen.Vanaf29 sep 2011 → 30 sep 2015Financiering: FWO mandaten
- Het Rev-afhankelijke nucleocytoplasmatisch mRNA-transport als nieuw doelwit voor anti-HIV therapieVanaf1 jan 2011 → 2 jun 2015Financiering: IWT persoonsgebonden financ. - strategische onderzoeksbeurzen
- Virale infecties: moleculaire inzichten, doel voor interventie en medicatie ontwikkelingVanaf1 nov 2010 → 31 okt 2018Financiering: BOF - Geconcert. Onderzoeksacties vanaf 1994
- Mechanistische studie van virus entry en replicatie. Een fundamentele benadering voor de ontwikkeling van nieuwe en specifieke antivirale chemotherapeutica.Vanaf1 jan 2010 → 31 dec 2014Financiering: BOF - Geconcert. Onderzoeksacties vanaf 1994
- Effect van Mycoplasma-enzymen op de antivirale en anti-kanker activiteit van nucleoside-analogen.Vanaf1 jun 2008 → 2 dec 2013Financiering: IWT persoonsgebonden financ. - strategische onderzoeksbeurzen
Publicaties
1 - 10 van 546
- Synthesis and Evaluation of Prodrugs of alpha-Carboxy Nucleoside Phosphonates(2022)
Auteurs: Jan Balzarini
- Enantiocontrolled Preparation of Upsilon-Substituted Cyclohexenones: Synthesis and Kinase Activity Assays of Cyclopropyl-Fused Cyclohexane Nucleosides(2022)
Auteurs: Jan Balzarini
- Benzothiazole Derivatives as Multifunctional Antioxidant Agents for Skin Damage: Structure-Activity Relationship of a Scaffold Bearing a Five-Membered Ring System(2022)
Auteurs: Jan Balzarini, Sandra Liekens
- Skin Damages-Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System(2020)
Auteurs: Jan Balzarini, Sandra Liekens
- Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold(2020)
Auteurs: Jan Balzarini, Sandra Liekens
- Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization(2020)
Auteurs: Jan Balzarini, Dominique Schols
- Synthesis, characterization and anti-HIV activity of polycarboxylic [60]fullerene derivatives obtained in the reaction of C60Cl6 with a hydroquinone ethere(2020)
Auteurs: Jan Balzarini, Dominique Schols
- Direct arylation of C60Cl6 and C70Cl8 with carboxylic acids: a synthetic avenue to water-soluble fullerene derivatives with promising antiviral activity(2020)
Auteurs: Jan Balzarini, Dominique Schols
Pagina's: 1179 - 1182 - Synthesis, Biological Evaluation and Ligand Based Pharmacophore Modeling of New Aromatic Thiosemicarbazones as Potential Anticancer Agents(2019)
Auteurs: Jan Balzarini
Pagina's: 139 - 149 - Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity(2019)
Auteurs: Sam Noppen, Sandra Liekens, Jan Balzarini
Pagina's: 390 - 398
Patenten
1 - 10 van 10
- Phosphonucleosides useful in the treatment of viral disorders (Inventor)
- Novel anti-cancer thiophene compounds (Inventor)
- Pradimicin derivatives for the treatment of diseases caused by kinetoplastids (Inventor)
- New pradimicin derivatives for the treatment of diseases caused by kinetoplastids (Inventor)
- Phosphonate nucleosides useful in the treatment of viral diseases (Inventor)
- Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine for use in the treatment of cancer (Inventor)
- Phosphonucleosides useful in the treatment of viral disorders (Inventor)
- Phosphonate nucleosides useful in the treatment of viral diseases (Inventor)
- Anti-cancer compounds (Inventor)
- 6-[2-(PHOSPHONOMETHOXY)ALKOXY] PYRIMIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY (Inventor)