Onderzoeker
Jan Félix
- Disciplines:Biofysica, Moleculaire en celbiologie, Medische biochemie en metabolisme, Laboratoriumgeneeskunde, Microbiologie, Systeembiologie, Plantenbiologie, Biochemie en metabolisme, Medicinale en biomoleculaire chemie
Affiliaties
- Vakgroep Biochemie en Microbiologie (Departement)
Lid
Vanaf7 sep 2010 → Heden
Projecten
1 - 2 of 2
- Structurele biologie van Interleukine-34, een nieuw cytokine ligand voor colony stimulating factor 1 receptor (CSF-1R)Vanaf1 okt 2011 → 30 sep 2015Financiering: BOF - Andere acties, FWO mandaten
- De structurele biologie van Interleukine 34, een nieuwe cytokine-ligand voor colony stimulating factor 1 receptor (CSF1R)Vanaf1 okt 2010 → 30 sep 2012Financiering: BOF - Nieuwe Onderzoeksinitiatieven
Publicaties
1 - 10 van 22
- EGOC inhibits TOROID polymerization by structurally activating TORC1(2023)
Auteurs: Manoël Prouteau, Clélia Bourgoint, Jan Félix, Lenny Bonadei, Yashar Sadian, Caroline Gabus, Savvas Savvides, Irina Gutsche, Ambroise Desfosses, Robbie Loewith
Pagina's: 273 - 285 - Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action(2022)
Auteurs: Katharina Weinhäupl, Marcos Gragera, M. Teresa Bueno-Carrasco, Rocío Arranz, Olga Krandor, Tatos Akopian, Raquel Soares, Eric Rubin, Jan Félix, Hugo Fraga
- AAA+ ATPases : structural insertions under the magnifying glass(2021)
Auteurs: Matthew Jessop, Jan Félix, Irina Gutsche
Pagina's: 119 - 128 - Structural basis of cytokine-mediated activation of ALK family receptors(2021)
Auteurs: Steven De Munck, Mathias Provost, Michiko Kurikawa, Ikuko Omori, Junko Mukohyama, Jan Félix, Yehudi Bloch, Omar Abdel-Wahab, J. Fernando Bazan, Akihide Yoshimi, et al.
Pagina's: 143 - 147 - Supramolecular assembly of the Escherichia coli LdcI upon acid stress(2021)
Auteurs: Matthew Jessop, Clarissa Liesche, Jan Félix, Ambroise Desfosses, Megghane Baulard, Virgile Adam, Angélique Fraudeau, Karine Huard, Grégory Effantin, Jean-Philippe Kleman, et al.
- Structural and functional analysis of the Francisella lysine decarboxylase as a key actor in oxidative stress resistance(2021)
Auteurs: Jan Félix, Claire Siebert, Julia Novion Ducassou, Jérôme Nigou, Pierre Simon Garcia, Angélique Fraudeau, Karine Huard, Caroline Mas, Céline Brochier-Armanet, Yohann Couté, et al.
- Proteolysis and multimerization regulate signaling along the two-component regulatory system AdeRS(2021)
Auteurs: Zhenlin Ouyang, Fang Zheng, Li Zhu, Jan Félix, Di Wu, Ke Wu, Irina Gutsche, Yi Wu, Peter M. Hwang, Junjun She, et al.
- Trimeric structure of the mouse Kupffer cell CU+2010type lectin receptor Clec4f(2020)
Auteurs: Zhenlin Ouyang, Jan Félix, Jinhong Zhou, Yingmei Pei, Bohan Ma, Peter M. Hwang, M. Joanne Lemieux, Irina Gutsche, Fang Zheng, Yurong Wen
Pagina's: 189 - 198 - Structure and assembly mechanism of the signaling complex mediated by human CSF-1 (vol 23, pg 1621, 2015)(2020)
Auteurs: Jan Félix, Steven De Munck, Kenneth Verstraete, Leander Meuris, Jonathan Elegheert, Savvas Savvides
- Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex(2020)
Auteurs: Matthew Jessop, Benoit Arragain, Roger Miras, Angélique Fraudeau, Karine Huard, Maria Bacia-Verloop, Patrice Catty, Jan Félix, Hélène Malet, Irina Gutsche