Onderzoeker
Lynn De Backer
- Disciplines:Nanobiotechnologie, Nanoschaalkarakterisering, Milieuveiligheid en gezondheid van nanotechnologie, Nanotechnologie niet elders geclassificeerd, Nanofotonica, Nanometrologie, Nanomaterialen, Andere farmaceutische wetenschappen niet elders geclassificeerd, Nanomanufacturing, Nanofabricage, -groei en zelfassemblage, Nano-elektromechanische systemen
Affiliaties
- Vakgroep Geneesmiddelenleer (Departement)
Lid
Vanaf17 sep 2010 → 3 sep 2017
Publicaties
1 - 10 van 13
- The alpha-adrenergic antagonist prazosin promotes cytosolic siRNA delivery from lysosomal compartments(2023)
Auteurs: Thijs Van de Vyver, Cristina Muntean, Iuliia Efimova, Dmitri Krysko, Lynn De Backer, Stefaan De Smedt, Koen Raemdonck
Pagina's: 142 - 158 - Cationic amphiphilic drugs boost the lysosomal escape of small nucleic acid therapeutics in a nanocarrier-dependent manner(2020)
Auteurs: Thijs Van de Vyver, Bram Bogaert, Lynn De Backer, Freya Joris, Roberta Guagliardo, Jelter Van Hoeck, Pieterjan Merckx, Srinivas Ramishetti, Dan Peer, Katrien Remaut, et al.
Pagina's: 4774 - 4791 - Nanocarrier lipid composition modulates the impact of pulmonary surfactant protein B (SP-B) on cellular delivery of siRNA(2019)
Auteurs: Roberta Guagliardo, Pieterjan Merckx, Agata Zamborlin, Lynn De Backer, Mercedes Echaide, Jesus Pérez-Gil, Stefaan De Smedt, Koen Raemdonck
- Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy(2018)
Auteurs: Pieterjan Merckx, Lynn De Backer, Lien Van Hoecke, Roberta Guagliardo, Mercedes Echaide, Pieter Baatsen, Bárbara Olmeda, Jésus Pérez-Gil, Koen Raemdonck
Pagina's: 236 - 246 - Repurposing cationic amphiphilic drugs as adjuvants to induce lysosomal siRNA escape in nanogel transfected cells(2018)
Auteurs: Freya Joris, Lynn De Backer, Thijs Van de Vyver, Chiara Bastiancich, Koen Raemdonck
Pagina's: 266 - 276 - Hitchhiking nanoparticles: reversible coupling of lipid-based nanoparticles to cytotoxic T lymphocytes(2016)
Auteurs: Laura Wayteck, Heleen Dewitte, Lynn De Backer, Karine Breckpot, Koen Raemdonck
Pagina's: 243 - 254 - Bio-inspired pulmonary surfactant-modified nanogels : a promising siRNA delivery system(2015)
Auteurs: Lynn De Backer, Kevin Braeckmans, Marc CA Stuart, Koen Raemdonck
Pagina's: 177 - 186 - Bio-inspired materials in drug delivery : exploring the role of pulmonary surfactant in siRNA inhalation therapy(2015)
Auteurs: Lynn De Backer, Alejandro Cerrada, Jesús Pérez-Gil, Koen Raemdonck
Pagina's: 642 - 650 - Hybrid pulmonary surfactant-coated nanogels mediate efficient in vivo delivery of siRNA to murine alveolar macrophages(2015)
Auteurs: Lynn De Backer, Thomas Naessens, Stefaan De Koker, Elisa Zagato, Johan Grooten, Koen Raemdonck
Pagina's: 53 - 63 - Exploring bio-inspired nanocomposites of nanogels and pulmonary surfactant for small interfering RNA delivery(2015)
Auteurs: Lynn De Backer