Onderzoeker
Sofie Demeyer
- Disciplines (Flanders Institute for Biotechnology):Analyse van next-generation sequence data, Celdood, Kankerbiologie
- Disciplines (KU Leuven):Systeembiologie
- Zie ook: Sofie Demeyer (Vlaams Instituut voor Biotechnologie)
Affiliaties
- Cools Lab (Onderzoeksgroep)
Lid
Vanaf1 jan 2017 → Heden - Laboratorium voor Moleculaire Biologie van Leukemie (VIB-KU Leuven) (Afdeling)
Lid
Vanaf12 mei 2014 → Heden
Projecten
1 - 1 of 1
- Combineren van CRISPR screening en single-cell RNA sequencing voor het ontrafelen van de mechanismen van T-cel acute lymfatische leukemieVanaf1 okt 2019 → HedenFinanciering: FWO mandaten, BOF - doctorale mandaten
Publicaties
11 - 20 van 35
- Monitoring of Leukemia Clones in B-cell Acute Lymphoblastic Leukemia at Diagnosis and During Treatment by Single-cell DNA Amplicon Sequencing(2022)
Auteurs: Sarah Meyers, Jolien De Bie, Lucienne Michaux, Barbara Dewaele, Nancy Boeckx, Anne Uyttebroeck, Kim De Keersmaecker, Johan Maertens, Heidi Segers, Jan Cools, et al.
- Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma(2021)
Auteurs: Sofie Demeyer, Jan Cools
Pagina's: 1040 - 1052 - Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia(2021)
Auteurs: Quentin Van Thillo, Jolien De Bie, Sofie Demeyer, Heidi Segers, Nancy Boeckx, Anne Uyttebroeck, Jan Cools
- Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified(2021)
Auteurs: Koen Debackere, Lukas Marcelis, Sofie Demeyer, Marlies Vanden Bempt, Gregor Verhoef, Lucienne Michaux, Thomas Tousseyn, Jan Cools, Daan Dierickx
- Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia(2021)
Auteurs: Sofie Demeyer, Inge Govaerts, Jolien De Bie, Lucienne Michaux, Johan Maertens, Anne Uyttebroeck, Kim De Keersmaecker, Nancy Boeckx, Heidi Segers, Jan Cools
Pagina's: 801 - 811 - The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia(2020)
Auteurs: Delphine Verbeke, Sofie Demeyer, Jolien De Bie, Anne Uyttebroeck, Nancy Boeckx, Kim De Keersmaecker, Johan Maertens, Heidi Segers, Jan Cools
Pagina's: 5747 - 5758 - Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia(2019)
Auteurs: Michaël Broux, Cristina PRIETO FERNANDEZ, Sofie Demeyer, Marlies Vanden Bempt, Inge Lodewijckx, Jan Cools
Pagina's: 1323 - 1336 - Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition(2019)
Auteurs: Charles De Bock, Inge Lodewijckx, Delphine Verbeke, David Nittner, Sofie Demeyer, James Dooley, Adrian Liston, Jan Cools, Bart De Strooper
- The Long Non-coding RNA Flatr Anticipates Foxp3 Expression in Regulatory T Cells(2018)
Auteurs: Aleksandra Brajic, Simon Bornschein, Sofie Demeyer, Jan Cools, James Dooley, Susan Schlenner, Adrian Liston
- The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models(2018)
Auteurs: Rocco Stirparo, Sofie Demeyer, Charles De Bock, Mardelle Atkins, Georg Halder, Bassem Hassan, Jan Cools