Onderzoeker
Sofie Demeyer
- Disciplines (Flanders Institute for Biotechnology):Analyse van next-generation sequence data, Celdood, Kankerbiologie
- Disciplines (KU Leuven):Systeembiologie
- Zie ook: Sofie Demeyer (Vlaams Instituut voor Biotechnologie)
Affiliaties
- Cools Lab (Onderzoeksgroep)
Lid
Vanaf1 jan 2017 → Heden - Laboratorium voor Moleculaire Biologie van Leukemie (VIB-KU Leuven) (Afdeling)
Lid
Vanaf12 mei 2014 → Heden
Projecten
1 - 1 of 1
- Combineren van CRISPR screening en single-cell RNA sequencing voor het ontrafelen van de mechanismen van T-cel acute lymfatische leukemieVanaf1 okt 2019 → HedenFinanciering: FWO mandaten, BOF - doctorale mandaten
Publicaties
21 - 30 van 35
- Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia(2018)
Auteurs: Marlies Vanden Bempt, Sofie Demeyer, Michaël Broux, Jolien De Bie, Simon Bornschein, Ellen Geerdens, Charles De Bock, Jan Cools
Pagina's: 271 - + - Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia(2018)
Auteurs: Jolien De Bie, Sofie Demeyer, Ellen Geerdens, Heidi Segers, Michaël Broux, Kim De Keersmaecker, Lucienne Michaux, Peter Vandenberghe, Thierry Voet, Nancy Boeckx, et al.
Pagina's: 1358 - 1369 - BCR-ABL1 positive B-ALL can undergo T-cell lineage shift to become CD19 negative T-ALL(2018)
Auteurs: Jolien De Bie, Sofie Demeyer, Heidi Segers, Lucienne Michaux, Peter Vandenberghe, Nancy Boeckx, Anne Uyttebroeck, Jan Cools
- Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T cell model system(2018)
Auteurs: Simon Bornschein, Sofie Demeyer, Rocco Stirparo, Carmen Vicente, Ellen Geerdens, Bart Ghesquière, Stein Aerts, Jan Cools, Charles De Bock
Pagina's: 941 - 951 - Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia(2018)
Auteurs: Sandrine Degryse, Charles De Bock, Sofie Demeyer, Inge Govaerts, Simon Bornschein, Delphine Verbeke, Jan Cools
Pagina's: 788 - 800 - HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development(2018)
Auteurs: Charles De Bock, Sofie Demeyer, Sandrine Degryse, Delphine Verbeke, Marlies Vanden Bempt, Ellen Geerdens, Simon Bornschein, Rik Gijsbers, Jan Cools
Pagina's: 616 - 631 - Mutant JAK3 signaling is increased by loss of wild type JAK3 or by acquiring secondary JAK3 mutations in T-ALL(2018)
Auteurs: Sandrine Degryse, Simon Bornschein, Charles De Bock, Marlies Vanden Bempt, Sofie Demeyer, Ellen Geerdens, Jan Cools
Pagina's: 421 - 425 - Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors(2016)
Auteurs: Sofie Demeyer, Jolien De Bie, Sandrine Degryse, Ellen Geerdens, Anne Uyttebroeck, Nancy Boeckx, Charles De Bock, Jan Cools
Pagina's: 2642 - 2654 - Generation of the Fip1l1-Pdgfra fusion gene using CRISPR/Cas genome editing(2016)
Auteurs: Marlies Vanden Bempt, Sofie Demeyer, Ellen Geerdens, Charles De Bock, Jan Cools
Pagina's: 1913 - 1916 - Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia(2016)
Auteurs: Sofie Demeyer, Jan Cools
Pagina's: 951 - 958