Onderzoeker
An Van Nuffel
- Trefwoorden:Geneeskunde
- Disciplines:Translationele wetenschappen, Klinische wetenschappen, Basiswetenschappen
Affiliaties
- Fysiologie (Departement)
Lid
Vanaf1 sep 2010 → 30 sep 2012 - Laboratorium voor Moleculaire en Cellulaire Therapie (Onderzoeksgroep)
Lid
Vanaf1 okt 2006 → 30 sep 2012 - Fysiologie (Departement)
Lid
Vanaf1 sep 2006 → 30 sep 2012
Publicaties
1 - 10 van 22
- Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma(2023)
Auteurs: Emiel A De Jaeghere, Sandra Tuyaerts, An Van Nuffel, Ann Belmans, Kris Bogaerts, Regina E. M. Baiden-Amissah, Lien Lippens, Peter Vuylsteke, Stéphanie Henry, xuan bich trinh, et al.
Pagina's: 475-491 - 159P Pembrolizumab, SBRT, and immunomodulation for recurrent and/or refractory cervical or endometrial carcinoma(2021)
Auteurs: Emiel De Jaeghere, An Van Nuffel, Lien Lippens, An Hendrix, Peter Vuylsteke, xuan bich trinh, Peter A Van Dam, Alex De Caluwé, Eline Naert, Koen Van de Vijver, et al.
Pagina's: 1449-1450 - Single-step antigen loading and maturation of dendritic cells through mRNA electroporation of a tumor-associated antigen and a TriMix of costimulatory molecules(2014)
Auteurs: Daphné Benteyn, An Van Nuffel, Sofie Wilgenhof
Pagina's: 3-15 - Design of an Optimized Wilms' Tumor 1 (WT1) mRNA Construct for Enhanced WT1 Expression and Improved Immunogenicity In Vitro and In Vivo(2013)
Auteurs: Daphné Benteyn, S. Anguille, Sandra Van Lint, Carlo Heirman, An Van Nuffel, Jurgen Corthals, S. Ochsenreither, Wim Waelput, Katrien Van Beneden, Karine Breckpot, et al.
- Modulation of regulatory T cell function by monocyte-derived dendritic cells matured through electroporation with mRNA encoding CD40 ligand, constitutively active TLR4, and CD70(2013)
Auteurs: Joeri J Pen, Brenda De Keersmaecker, Sarah Maenhout, An Van Nuffel, Carlo Heirman, Jurgen Corthals, D. Escors, Kris Thielemans, Karine Breckpot, Joeri L Aerts
Pagina's: 1976-1983 - A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients.(2013)
Auteurs: Sofie Wilgenhof, An Van Nuffel, Daphné Benteyn, Jurgen Corthals, Cindy Aerts, Carlo Heirman, Ivan Van Riet, Kris Thielemans, Bart Neyns
Pagina's: 2686-2693 - Characterization of CD8+ T-cell responses in the peripheral blood and skin injection sites of melanoma patients treated with mRNA electroporated autologous dendritic cells (TriMixDC-MEL)(2013)
Auteurs: Daphné Benteyn, An Van Nuffel, Sofie Wilgenhof, Jurgen Corthals, Carlo Heirman, Bart Neyns, Kris Thielemans
- Overcoming HLA restriction in clinical trials: Immune monitoring of mRNA-loaded DC therapy(2012)
Auteurs: An Van Nuffel, Sofie Wilgenhof, Kris Thielemans
Pagina's: 1392-1394 - Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient(2012)
Auteurs: An Van Nuffel, Daphné Benteyn, Sofie Wilgenhof, Jurgen Corthals, Carlo Heirman, Bart Neyns, Kris Thielemans
Pagina's: 1033-1043 - Dendritic cells loaded with mRNA encoding full-length tumor antigens prime CD4+ and CD8+ T cells in melanoma patients(2012)
Auteurs: An Van Nuffel, Daphné Benteyn, Sofie Wilgenhof, Lauranne Pierret, Jurgen Corthals, Carlo Heirman, Pierre Van Der Bruggen, Pierre Coulie, Bart Neyns, Kris Thielemans
Pagina's: 1063-1074