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Onderzoeker
Xavier Saelens
- Trefwoorden (Ghent University):Virologie, Vaccinologie, antivirale immuniteit
- Disciplines (Flanders Institute for Biotechnology):Analytische biochemie, Celdood en senescentie, Analyse van next-generation sequence data, Algemene diagnostiek
- Disciplines (Ghent University):Toegepaste immunologie, Ontdekking en evaluatie van geneesmiddelen niet elders geclassificeerd, Klinische trials, Biofarmaceutica, In vitro testen, Niet-klinische studies, Dierlijke immunologie, Transcriptie en translatie, Vaccins, Moleculaire en celbiologie niet elders geclassificeerd, Virologie
- Zie ook: Xavier Saelens (Universiteit Gent)
Affiliaties
- Vakgroep Biochemie en Microbiologie (Departement)
Lid
Vanaf1 okt 2018 → Heden - Saelens Lab (Onderzoeksgroep)
Verantwoordelijke
Vanaf1 jan 2017 → Heden - Vakgroep Biomedische Moleculaire Biologie (Departement)
Lid
Vanaf1 jan 1996 → 30 sep 2018 - Vakgroep Plantenbiotechnologie en Bio-informatica (Departement)
Lid
Vanaf1 jan 1993 → 31 dec 1995
Projecten
1 - 6 of 6
- Evolvable and rapidly adaptable monobodies: a broad-spectrum antiviral platform.Vanaf1 jan 2024 → HedenFinanciering: Andere Eu-programma's en intiatieven
- VIB Grant for Saelens Lab_Period:2022-01-01-2026-12-31Vanaf1 jan 2022 → HedenFinanciering: VOI - Projectmatig onderzoek
- Pichia for pandemic readiness VHH-Fc antibodiesVanaf1 dec 2021 → 29 feb 2024Financiering: Buitenl. stichtingen, fondsen e.d. met wet. oogmerk
- ExeVir's XVR011, a best in class nanobody-based biology that broadly neutralizes SARS-COV-1 and SARS-COV-2Vanaf1 dec 2021 → 30 nov 2022Financiering: Andere Eu-programma's en intiatieven
- 'Evaluation of ratioNally Designed Influenza vaccines’ — ‘ENDFLU’Vanaf1 aug 2020 → HedenFinanciering: Andere Eu-programma's en intiatieven
- VIB Grant for Saelens Lab_Period:2017-01-01-2021-12-31Vanaf1 jan 2017 → 31 dec 2021Financiering: VOI - Projectmatig onderzoek
Publicaties
1 - 10 van 85
- Systematic review and meta-analysis of genome-wide pooled CRISPR screens to identify host factors involved in influenza A virus infection.(2024)
Auteurs: Annabel Maes, Alexander Botzki, Janick Mathys, Francis Impens, Xavier Saelens
Pagina's: e-pub - Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted.(2024)
Auteurs: Bert Schepens, Sieglinde De Cae, Koen Sedeyn, Hannah Eeckhaut, Daria Fijalkowska, Kenny Roose, Nico Callewaert, Han Remaut, Xavier Saelens
Pagina's: 104960 - A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein.(2024)
Auteurs: Marlies Ballegeer, Shubham Pandey, Xavier Saelens
Pagina's: e-pub - Promises and challenges of single-domain antibodies to control influenza.(2024)
Auteurs: Arne Matthys, Xavier Saelens
Pagina's: 105807 - Development of Digital Droplet PCR Targeting the Influenza H3N2 Oseltamivir-Resistant E119V Mutation and Its Performance through the Use of Reverse Genetics Mutants.(2023)
Auteurs: Laura Van Poelvoorde, Xavier Saelens
Pagina's: 2521-2532 - Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins.(2023)
Auteurs: Francis Impens, Xavier Saelens, Kris Gevaert
Pagina's: 450 - Rethinking IL-1 Antagonism in Respiratory Viral Infections: A Role for IL-1 Signaling in the Development of Antiviral T Cell Immunity.(2023)
Auteurs: Marlies Ballegeer, Xavier Saelens
Pagina's: 15770 - Epidemiology of influenza over a ten-year period in Belgium: overview of the historical and current evidence.(2023)
Auteurs: Xavier Saelens
Pagina's: 271 - GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery.(2023)
Auteurs: Loes van Schie, Wander Van Breedam, Charlotte Roels, Bert Schepens, Iebe Rossey, Karel Thooft, Xavier Saelens, Nico Callewaert
Pagina's: 2210709 - Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair.(2023)
Auteurs: Marlies Ballegeer, Xavier Saelens
Pagina's: eadg2829
Patenten
1 - 10 van 10
- SARBECOVIRUS BINDERS (Inventor)
- CORONA VIRUS BINDERS (Inventor)
- CORONA VIRUS BINDERS (Inventor)
- PAN-SPECIFIC CORONA VIRUS BINDERS (Inventor)
- SARBECOVIRUS BINDERS (Inventor)
- ANTIBODY COMPOSITIONS FOR TREATMENT OF CORONA VIRUS INFECTION (Inventor)
- CORONA VIRUS BINDERS (Inventor)
- Methods of Generating Broadly Protective Vaccine Compositions Comprising Neuraminidase (Inventor)
- Methods of Generating Broadly Protective Vaccine Compositions Comprising Neuraminidase (Inventor)
- MIXED-LINEAGE KINASE DOMAIN-LIKE PROTEIN IN IMMUNOTHERAPEUTIC CANCER CONTROL (Inventor)