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Octrooi

Compositions comprising adamts13 for use in methods for the recanalization of occluded blood vessels in an infarction

Provided herein are methods for recanalization of occluded blood vessels in a subject having an infarction. The method includes a step of administering to the subject a therapeutically effective amount of isolated ADAMTS13 protein at particular dosages and ranges of times after detection of the infarction. As described herein, ADAMTS13 advantageously recanalizes occluded blood vessels and reduces infarction size, even when administered a prolonged period after stable occlusion. Accordingly, such methods and compositions are useful for the treatment of infractions caused by blood vessel occlusion.
Octrooi-publicatienummer: WO2016191565
Jaar aanvraag: 2016
Jaar toekenning: 2017
Jaar van publicatie: 2016
Status: Aangevraagd
Technologiedomeinen: Farmaceutische producten
Gevalideerd voor IOF-sleutel: Ja
Toegewezen aan: Associatie KULeuven