Mono- or di-substituted indole derivatives as dengue viral replication inhibitors

The present invention relates to mono- or di-substituted indole compounds, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.

Octrooi-publicatienummer: EP3294738

Jaar aanvraag: 2021

Jaar toekenning: 2021

Jaar van publicatie: 2021

Status: Toegewezen

Technologiedomeinen: Organische fijne chemie

Gevalideerd voor IOF-sleutel: Ja

Toegewezen aan: Associatie KULeuven, Associatie KULeuven, Associatie KULeuven