Dosimetry and Monte Carlo modelling of the Papillon plus contact X-ray brachytherapy device

PURPOSE: This study aimed to develop and validate a Monte Carlo (MC) model for the Papillon + contact x-ray brachytherapy (CXB) device, producing 50 kilovolt (kV) X-rays, specifically focusing on its application with a 25 mm diameter rectal applicator for contact therapy. MATERIAL AND METHODS: The validation process involved depth dose and transverse dose profile measurements using EBT3 gafchromic films positioned in a plastic water low energy range phantom. The half-value layer (HVL) was further measured and derived from the simulated X-ray spectra. RESULTS: Excellent agreement within +/- 2% was achieved between the measured and simulated on-axis depth dose curves for the 25 mm rectal applicator. Transverse dose profile measurements showed a high level of agreement between the simulation and measurements, on average 3.1% in contact with the applicator at the surface of the phantom and on average 1.7% at 10 mm depth. A close agreement within 5.5% was noticed concerning the HVL between the measurement and simulation. The simulated gamma spectra and 2D-dose distribution demonstrated a soft X-ray energy spectrum and a uniform dose distribution in contact with the applicator. CONCLUSIONS: An MC model was successfully developed for the Papillon + eBT device with a 25 mm diameter rectal applicator. The validated model, with its demonstrated accuracy in depth dose and transverse dose profile simulations, is a valuable tool for quality assurance and patient safety and, in a later phase, may be used for treatment planning, dose calculations and tissue inhomogeneity corrections. (c) 2024 American Brachytherapy Society. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

Jaar van publicatie:2024

Trefwoorden:Monte Carlo modelling, Contact X-ray brachytherapy, Papillon treatment, Rectal cancer, Hematologie en oncologie, Radiologie en nucleaire geneeskunde

Toegankelijkheid:Embargoed