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Site-specific labeling of his-tagged Nanobodies with 99mTc: A practical guide

Boekbijdrage - Hoofdstuk

99mTc-tricarbonyl chemistry provides an elegant technology to site-specifically radiolabel histidine-tagged biomolecules. Considering their unique biochemical properties, this straightforward technology is particularly suited for Nanobodies. This chapter gives a detailed guide to generate highly specific Nanobody-derived radiotracers for both in vitro binding studies and in vivo molecular imaging.
Boek: Single Domain Antibodies
Series: Methods in Molecular Biology
Pagina's: 485-490
Aantal pagina's: 6
ISBN:978-1-61779-967-9
Jaar van publicatie:2012
Trefwoorden:Nanobodies
  • ORCID: /0000-0001-9220-4833/work/88545658
  • ORCID: /0000-0002-1773-8664/work/62884425
  • ORCID: /0000-0001-9006-1074/work/62359749
  • ORCID: /0000-0002-8739-6137/work/61349048
  • ORCID: /0000-0002-6895-4260/work/61247288
  • ORCID: /0000-0002-4301-5902/work/61226872
  • DOI: https://doi.org/10.1007/978-1-61779-968-6_30
  • Scopus Id: 84871872770