Publicaties

Laser sintering is evolving towards a genuine manufacturing technique for volume production and mass customized products. However, variability in part quality has to be reduced further to enable its use for high demanding and critical end-use applications. High volume and mass customized manufacturing impose the need for a fast and flexible measurement instrument, to automatically assess the overall part quality, which is currently not available ...

Dentoalveolar tissue engineering is an emerging yet challenging field, considering the lack of suitable materials and difficulty to produce patient-specific hydrogel scaffolds. The present paper aims to produce a 3D printable and tuneable biomaterial by copolymerizing a synthesized water-soluble chitosan derivative called maleic an hydride grafted chitosan (MA-C) with gelatin using genipin, a natural crosslinking agent. Development and testing ...

Acrylate-based photo-cross-linked poly(ε-caprolactone) (PCL) tends to show low elongation and strength. Incorporation of osteo-inductive hydroxyapatite (HAp) further enhances this effect, which limits its applicability in bone tissue engineering. To overcome this, the thiol-ene click reaction is introduced for the first time in order to photo-cross-link PCL composites with 0, 10, 20, and 30 wt % HAp nanoparticles. It is demonstrated that the ...

Viscoelastic hydrogels are gaining interest as they possess necessary requirements for bioprinting and injectability. By means of reversible, dynamic covalent bonds, it is possible to achieve features that recapitulate the dynamic character of the extracellular matrix. Dually cross-linked and double-network (DN) hydrogels seem to be ideal for the design of novel biomaterials and bioinks, as a wide range of properties required for mimicking ...

A flexor tendon injury is acquired fast and is common for athletes, construction workers, and military personnel among others, treated in the emergency department. However, the healing of injured flexor tendons is stretched over a long period of up to 12 weeks, therefore, remaining a significant clinical problem. Postoperative complications, arising after traditional tendon repair strategies, include adhesion and tendon scar tissue formation, ...

Recently, poly(nonamethylene terephthalate) (PAT(n=9)) and poly(decamethylene terephthalate) (PAT(n=10))
gained increasing interest since it was reported to exhibit enhanced endothelial cell adhesion and viability
compared to other poly(alkylene terephthalate) (PAT) analogues. Enhanced endothelial cell interactivity is of
particular interest when targeting cardiovascular applications, more specifically, for creating synthetic ...

Membrane chromatography is recognised as a potential solution to streamline downstream processing for protein purification, where ion exchange membrane chromatography (IEMC) as a polishing step to remove impurities has been successfully demonstrated in small scales. Despite limited commercial adoption in large-scale production, the concept of IEMC attracts many interests and tremendous progress is made. To fill the review gap for advancements in ...

Solid-state batteries (SSBs) are gaining attention as they promise to provide better safety and a higher energy density than conventional liquid electrolyte batteries. Solid polymer electrolytes (SPEs) are promising candidates due to their flexibility providing better interfacial contact between electrodes and the electrolyte. However, SPEs exhibit very low ionic conductivity at ambient temperatures, which prevents their practical use in ...

The synthesis of a supramolecular polymer network based on ureidopyrimidinone (UPy) is demonstrated starting from a low-molecular weight polybutadiene (PB) polymer, which was modified with UPy quadruple hydrogen-bonding motifs through UV-initiated thiol-ene chemistry under ambient conditions. Here, the UPy units contain a branched alkyl side chain rather than a methyl group, as is the case in most literature examples. The sterically demanding ...