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Re-challenge with catumaxomab in patients with malignant ascites: results from the SECIMAS study KU Leuven

Klaus Pietzner, Ignace Vergote, Armando Santoro, Radoslav Chekerov, Frederik Marmé, Per Rosenberg, Holger Martinius, Hilke Friccius-Quecke, Jalid Sehouli
Malignant ascites is a common phenomenon in cancer patients. It poses a great challenge to the clinician, because of limited treatment options and strong impairment of the quality of life of the often palliative patients. The SECIMAS study investigated the feasibility of a re-challenge with four catumaxomab intraperitoneal infusions in patients who had already received a first cycle of four infusions in the phase III CASIMAS study, which ...