Detection of single nucleotide polymorphisms in virus genomes assembled from high-throughput sequencing data: large-scale performance testing of sequence analysis strategies Instituut voor Landbouw-, Visserij- en Voedingsonderzoek
Recent developments in high-throughput sequencing (HTS) technologies and bioinformatics have drastically changed research on viral pathogens, especially for virus discovery and monitoring. Indeed, proper monitoring of the viral population requires information on the different isolates circulating in the studied area. For this purpose, HTS technologies have greatly facilitated the sequencing of new genome sequences of the detected viruses and ...