Publicaties

Background and purpose: A dosimetry audit program based on alanine electron paramagnetic resonance (EPR) and radiochromic film dosimetry, may be a valuable tool for monitoring and improving the quality of lung stereotactic body radiotherapy (SBRT). The aim of this study was to report the initial, independent assessment of the dosimetric accuracy for lung SBRT practice using these dosimeters in combination with a novel phantom design. Materials ...

S3191 Physics-Detectors, dose measurement and phantoms ESTRO 2024 allows BP10 to be versatilely used within a wide range of clinical scenarios, and particularly in stereotactic radiosurgery.

Purpose/Objective: Four-dimensional computed tomography (4DCT) has revolutionized the radiation therapy field by allowing visualization and tracking of movements in the target volume and organs at risk, leading to more accurate treatment procedures. However, the image quality and accuracy of quantitative information could be affected by severe artifacts arising from regular or irregular breathing and motion artifacts. These image quality ...

Background and purpose: In radiotherapy, the image quality of four-dimensional computed tomography (4DCT) is often degraded by artifacts resulting from breathing irregularities. Quality assurance mostly employ simplistic phantoms, not fully representing complexities and dynamics in patients. 3D-printing allows for design of highly customized phantoms. This study aims to validate the proof-of-concept of a realistic dynamic thorax phantom and its ...

PURPOSE: This study aimed to develop and validate a Monte Carlo (MC) model for the Papillon + contact x-ray brachytherapy (CXB) device, producing 50 kilovolt (kV) X-rays, specifically focusing on its application with a 25 mm diameter rectal applicator for contact therapy. MATERIAL AND METHODS: The validation process involved depth dose and transverse dose profile measurements using EBT3 gafchromic films positioned in a plastic water low energy ...

Background: In 2021, a Technical Meeting was hosted by the International Atomic Energy Agency (IAEA) where it was recommended that a standardized method for assessing the accuracy of film dose calculations should be established. Purpose: To design an audit that evaluates the accuracy of film dosimetry processes. To propose a framework for identifying out-of-tolerance results and to perform an international pilot study to test the audit design. ...

Background Plane-parallel ionization chambers are the recommended secondary standard systems for clinical reference dosimetry of electrons. Dosimetry in high dose rate and dose-per-pulse (DPP) is challenging as ionization chambers are subject to ion recombination, especially when dose rate and/or DPP is increased beyond the range of conventional radiotherapy. The lack of universally accepted models for correction of ion recombination in UDHR is ...

Radiation therapy (RT) is an essential treatment modality for cancer care and cure. Over the years, radiation treatments have become more complex and more computerized leading to highly precise treatment approaches maximising loco-regional control while minimizing toxicity. Safe and effective radiotherapy delivery however requires the implementation of adapted quality assurance (QA) programs and integral quality management (QM) systems, ...

Objective. A novel solution is required for accurate 3D bioluminescence tomography (BLT) based glioblastoma (GBM) targeting. The provided solution should be computationally efficient to support real-time treatment planning, thus reducing the x-ray imaging dose imposed by high-resolution micro cone-beam CT. Approach. A novel deep-learning approach is developed to enable BLT-based tumor targeting and treatment planning for orthotopic rat GBM ...