Publicaties
Bridging the HIV treatment gap in Nigeria: examining community antiretroviral treatment models Instituut voor Tropische Geneeskunde
Introduction: Significant gaps persist in providing HIV treatment to all who are in need. Restricting care delivery to healthcare facilities will continue to perpetuate this gap in limited resource settings. We assessed a large-scale community-based programme for effectiveness in identifying people living with HIV and linking them to antiretroviral treatment.
Methods: A retrospective secular trend study of 14 high burden local ...
Association between single-nucleotide polymorphisms in HLA alleles and human immunodeficiency virus type 1 viral load in demographically diverse, antiretroviral therapy-naive participants from the strategic timing of antiRetroviral treatment trial Instituut voor Tropische Geneeskunde
The impact of variation in host genetics on replication of human immunodeficiency virus type 1 (HIV-1) in demographically diverse populations remains uncertain. In the current study, we performed a genome-wide screen for associations of single-nucleotide polymorphisms (SNPs) to viral load (VL) in antiretroviral therapy-naive participants (n = 2440) with varying demographics from the Strategic Timing of AntiRetroviral Treatment (START) trial. ...
The effect of highly active antiretroviral treatment on viral load and antiretroviral drug levels in breast milk [research letter] Instituut voor Tropische Geneeskunde
Five-year immunological outcome of highly active antiretroviral treatment in a clinical setting: results from a single HIV treatment centre Instituut voor Tropische Geneeskunde
Integrated cryptococcal antigen screening and pre-emptive treatment prior to initiation of antiretroviral treatment in Cambodia Instituut voor Tropische Geneeskunde
Monitoring for treatment failure in patients on first-line antiretroviral treatment in resource-constrained settings Instituut voor Tropische Geneeskunde
Guidance modules on antiretroviral treatments. Module 4. Safe and effective use of antiretrovirals Instituut voor Tropische Geneeskunde
Does timing of antiretroviral treatment influence treatment outcomes of visceral leishmaniasis in Northwest Ethiopia? Instituut voor Tropische Geneeskunde
Background: Visceral leishmaniasis (VL) patients with HIV co-infection should receive antiretroviral treatment (ART). However, the best timing for initiation of ART is not known. Among such individuals, we assessed the influence of ART timing on VL outcomes.
Methods: A retrospective cohort study was conducted in Northwest Ethiopia among VL patients starting ART between 2008 and 2015. VL outcomes were assessed by the twelfth month of ...
Challenges, successes and patterns of enrolment in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial Instituut voor Tropische Geneeskunde
OBJECTIVES: The aim of this report is to describe the challenges, successes and patterns of enrolment in the Strategic Timing of AntiRetroviral Treatment (START) study.
METHODS: START is a collaboration of many partners with central coordination provided by the protocol team, the statistical and data management centre (SDMC), the International Network for Strategic Initiatives in Global HIV Trials (INSIGHT) network leadership, ...