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TOGETHER project to increase understanding of the HIV epidemic among sub-Saharan African migrants: protocol of community-based participatory mixed-method studies Instituut voor Tropische Geneeskunde Universiteit Antwerpen

Jasna Loos, Beatrijs Vuylsteke, Lazare Manirankunda, J Deblonde, Ilse Kint, Fiona Namanya, Catharina Fransen, Robert Colebunders, Marie Laga, Dorothy Adobea, et al.
Background: Sub-Saharan African Migrants (SAM) are the second largest group affected by HIV/AIDS in Belgium and the rest of Western Europe. Increasing evidence shows that, more than previously thought, SAM are acquiring HIV in their host countries. This calls for a renewed focus on primary prevention. Yet, knowledge on the magnitude of the HIV epidemic among SAM (HIV prevalence estimates and proportions of undiagnosed HIV infections) and ...

Contrasting benefits of different artemisinin combination therapies as first-line malaria treatments using model-based cost-effectiveness analysis Instituut voor Tropische Geneeskunde

L.C. Okell, M. Cairns, J.T. Griffin, N.M. Ferguson, J. Tarning, G. Jagoe, P. Hugo, M. Baker, D'Alessandro, T. Bousema, et al.
There are currently several recommended drug regimens for uncomplicated falciparum malaria in Africa. Each has different properties that determine its impact on disease burden. Two major antimalarial policy options are artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DHA-PQP). Clinical trial data show that DHA-PQP provides longer protection against reinfection, while AL is better at reducing patient infectiousness. Here we ...

Community empowerment and involvement of female sex workers in targeted sexual and reproductive health interventions in Africa: a systematic review Instituut voor Tropische Geneeskunde Universiteit Gent

Lizzie Moore, Matthew F Chersich, Richard Steen, Sushena Reza-Paul, Ashar Dhana, Beatrijs Vuylsteke, YVES LAFORT, Fiona Scorgie

BACKGROUND: Female sex workers (FSWs) experience high levels of sexual and reproductive health (SRH) morbidity, violence and discrimination. Successful SRH interventions for FSWs in India and elsewhere have long prioritised community mobilisation and structural interventions, yet little is known about similar approaches in African settings. We systematically reviewed community empowerment processes within FSW SRH projects in Africa, and ...

Doctors and vampires in sub-Saharan Africa Instituut voor Tropische Geneeskunde KU Leuven Vrije Universiteit Brussel Universiteit Gent

Koen Peeters, Joan Muela Ribera, Annette Erhart, Sarah Hoibak, Raffaella Ravinetto, Charlotte Gryseels, Susan Dierickx, O'Neill, Susanna Hausmann Muela, Umberto D'Alessandro, et al.

Collecting blood samples from individuals recruited into clinical research projects in sub-Saharan Africa can be challenging. Strikingly, one of the reasons for participant reticence is the occurrence of local rumors surrounding "blood stealing" or "blood selling." Such fears can potentially have dire effects on the success of research projects--for example, high dropout rates that would invalidate the trial's results--and have ethical ...