Publicaties
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Understanding the uptake of diagnostics for sustainable gastrointestinal nematode control by European dairy cattle farmers : a multi-country cross-sectional study Universiteit Gent
Subclinical nematode parasitism affects activity and rumination patterns in first-season grazing cattle Universiteit Gent
Sickness behaviour has been suggested as an applicable indicator for monitoring disease. Deviating feeding behaviour and activity can provide information about animals' health and welfare status. Recent advances in sensor technology enable monitoring of such behaviours and could potentially be utilized as an indicator of gastrointestinal nematode (GIN) infections. This study investigated activity and rumination patterns in first-season grazing ...
Evaluation of a Cooperia oncophora double-domain ASP-based vaccine against Cooperia spp. infections in cattle and sheep Universiteit Gent
A double-domain activation-associated secreted protein (dd-Co-ASP) isolated from the bovine small intestinal parasite Cooperia oncophora was previously shown to be an effective vaccine candidate to protect calves against a homologous challenge infection. The aim of this study was to investigate whether the dd-Co-ASP protein, purified from a Belgian C. oncophora isolate, would offer protection against a C. oncophora isolate from the southern ...
Survey design to monitor drug efficacy for the control of soil-transmitted helminthiasis and schistosomiasis Universiteit Gent
Background. Control of soil-transmitted helminthiasis and schistosomiasis relies heavily on regular preventive chemotherapy. Monitoring drug efficacy is crucial to provide early warning of treatment failures. The World Health Organization (WHO) recommends a survey design in which only egg-positive individuals are retested after treatment. Although this practice makes more efficient use of resources, it may lead to biased drug efficacy estimates. ...
Characterization of the β-tubulin gene family in Ascaris lumbricoides and Ascaris suum and its implication for the molecular detection of benzimidazole resistance Universiteit Gent
Biology and epidemiology of gastrointestinal nematodes in cattle Universiteit Gent
This article reviews the basics of gastrointestinal nematode biology and pathophysiology in cattle and describes how gastrointestinal nematode epidemiology is driven by environmental, host, and farm economic determinants. Adverse effects from gastrointestinal nematodes on their hosts are caused by tissue damage, nutrient absorption, immunopathologic effects, and reduced food intake induced by hormonal changes. Weather and microenvironmental ...
Evaluation of the therapeutic efficacy of praziquantel against schistosomes in seven countries with ongoing large-scale deworming programs Universiteit Gent
100 Questions in livestock helminthology research Universiteit Gent
An elicitation exercise was conducted to collect and identify pressing questions concerning the study of helminths in livestock, to help guide research priorities. Questions were invited from the research community in an inclusive way. Of 385 questions submitted, 100 were chosen by online vote, with priority given to open questions in important areas that are specific enough to permit investigation within a focused project or programme of ...
Comparative analysis of the immune responses induced by native versus recombinant versions of the ASP-based vaccine against the bovine intestinal parasite Cooperia oncophora Universiteit Gent
The protective capacities of a native double-domain activation-associated secreted protein (ndd-ASP)-based vaccine against the cattle intestinal nematode Cooperia oncophora has previously been demonstrated. However, protection analysis upon vaccination with a recombinantly produced antigen has never been performed. Therefore, the aim of the current study was to test the protective potential of a Pichia-produced double-domain ASP (pdd-ASP)-based ...