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Sero-prevalence of Brucella abortus among dairy cattle and buffaloes in Pothohar plateau, Pakistan Instituut voor Tropische Geneeskunde
Abcès hépatique amibien contract‚ en Inde avec confirmation du diagnostic par PCR Instituut voor Tropische Geneeskunde
Ethical research is grounded in quality data: a clinical data management workshop in Varanasi Instituut voor Tropische Geneeskunde
Village health workers in Bihar, India: an untapped resource in the struggle against kala-azar Instituut voor Tropische Geneeskunde
INTRODUCTION: In 2005 a visceral leishmaniasis (VL) elimination initiative was launched on the Indian subcontinent; important components of early case finding and treatment are entrusted to the primary health care system (PHC). In an earlier study in Bihar, India, we discovered some major shortcomings in implementation, in particular related to monitoring of treatment and treatment outcomes. These shortcomings could be addressed through ...
Comparison of visceral leishmaniasis diagnostic antigens in African and Asian Leishmania donovani reveals extensive diversity and region-specific polymorphisms Instituut voor Tropische Geneeskunde
BACKGROUND: Visceral leishmaniasis (VL), caused by infection with complex, remains a major public health problem in endemic regions of South Asia, East Africa, and Brazil. If untreated, symptomatic VL is usually fatal. Rapid field diagnosis relies principally on demonstration of anti- antibodies in clinically suspect cases. The rK39 immunochromatographic rapid diagnostic test (RDT) is based on rK39, encoded by a fragment of a kinesin-related ...
Seroprevalence and risk factors associated with Brucellosis as a professional hazard in Pakistan Instituut voor Tropische Geneeskunde
The present study was conducted to determine the seroprevalence and identify risk factors associated with brucellosis in humans at high risk in the Potohar plateau of northeastern Pakistan. A total of 262 serum samples were collected from persons of different occupational groups: veterinary personnel, milkers, abattoir workers, livestock farmers, and others (drivers, security guards, housewives). Data related to gender, age, occupation, contact ...
Understanding the burden of disease in Nepal: a call for local evidence Instituut voor Tropische Geneeskunde
The burden of disease, most commonly expressed in terms of Disability-Adjusted Life Years, has become a crucial component in decision making processes within the health sector. In Nepal, however, burden of disease estimates are scarce and lack representativeness. To improve our understanding of the burden of disease in Nepal and thereby increase the efficiency of health policies, there is an urgent need to strengthen thelocal evidencebased. All ...
Complexities in using sentinel pigs to study Taenia solium transmission dynamics under field conditions Instituut voor Tropische Geneeskunde
The transmission dynamics of the pork tapeworm, Taenia solium, remain a matter of research and debate. In a longitudinal field study performed in southeastern Nepal, 18 sentinel pigs were serologically monitored to study the field kinetics of Taenia antigens and anti-T. solium antibodies. At the end of the twelve months' study period, necropsy was performed and suspected lesions were subjected to molecular identification of the Taenia species. ...
The household costs of visceral leishmaniasis care in south-eastern Nepal Instituut voor Tropische Geneeskunde
BACKGROUND AND OBJECTIVES: Visceral leishmaniasis (VL) is an important public health problem in south-eastern Nepal affecting very poor rural communities. Since 2005, Nepal is involved in a regional initiative to eliminate VL. This study assessed the economic impact of VL on households and examined whether the intensified VL control efforts induced by the government resulted in a decrease in household costs. METHODS: Between August and September ...