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Increased detection of smear-negative pulmonary tuberculosis by GeneXpert MTB/RIF (R) assay after bleach concentration Universiteit Antwerpen

Mulualem Tadesse, Dossegnaw Aragaw, Leen Rigouts, Gemeda Abebe
Objective/background: The GeneXpert MTB/RIF assay (Xpert) was endorsed as the initial diagnostic tool in people suspected of human immunodeficiency virus-associated or drug-resistant tuberculosis (TB). However, information regarding the performance of Xpert for diagnosing smear-negative TB in high burden settings remains limited. We evaluated the diagnostic accuracy of Xpert and the impact of bleach concentration on the performance of Xpert ...

Improving the diagnosis of tuberculosis in hard to diagnose populations : clinical evaluation of GeneXpert MTB/RIF and alternative approaches in Ethiopia Instituut voor Tropische Geneeskunde

Mulualem Tadesse Jano
Background: The GeneXpert MTB/RIF® assay (Xpert MTB/RIF) was endorsed as the initial diagnostic tool in people suspected of HIV-associated or drug resistant tuberculosis (TB). However, information regarding the performance of Xpert for diagnosing smear-negative TB in high burden settings remains limited. We evaluated the diagnostic accuracy of Xpert MTB/RIF and the impact of bleach-concentration on the performance of Xpert MTB/RIF using ...