Publicaties
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Prilling of fatty acids as a continuous process for the development of controlled release multiparticulate dosage forms Universiteit Hasselt Universiteit Gent
In this study, prilling was evaluated as a technique for the development of multiparticulate dosage forms using the fatty acids, stearic acid, and behenic acid as potential matrix formers to control the release of metoprolol tartrate (MPT), a highly water soluble drug. The in vitro drug release was dependent on the drug load, type of fatty acid, and pH of the dissolution medium. Higher drug loads resulted in faster release with behenic acid ...
Prilling of fatty acids as innovative technology for oral controlled release multiple-unit systems Universiteit Gent
Prilling represents an innovative technology for continuous particle processing and has been intensively used for the production of urea pellets. The process converts a molten liquid into droplets followed by cooling of the droplets in a prilling tower, generating solid spherical particles with uniform size distribution. Up until now, only a few studies evaluated the suitability of the prilling technique for pharmaceutical applications. ...
Continuous twin screw granulation of controlled release formulations with various HPMC grades Universiteit Gent
Development of a controlled release formulation by continuous twin screw granulation : influence of process and formulation parameters Universiteit Gent
Fatty acids for controlled release applications: a comparison between prilling and solid lipid extrusion as manufacturing techniques Universiteit Gent
A novel malonamide Periodic Mesoporous Organosilica (PMO) for controlled ibuprofen release Universiteit Gent
Active Barrier Coating for Packaging Paper with Controlled Release of Sunflower Oils Universiteit Hasselt
The use of paper as a sustainable packaging material is favored, but it lacks sufficient barrier properties in terms of water repellence and oil resistance. Novel approaches consider active packaging materials or coatings with controlled release providing additional functionality for delivery of specific components to the surface. In this study, the development of a waterborne coating with organic nanoparticles and encapsulated sunflower oils is ...
Active coating for packaging papers with controlled thermal release of encapsulated plant oils Universiteit Hasselt
The surface properties and water repellence of paper substrates can be tuned by a waterborne nanoparticle coating containing hybrid organic nanoparticles with encapsulated vegetable oils. In particular, the release of oil from the deposited nanoparticle capsules can be activated upon thermal heating. The specific release tempera-ture allows to control the amount of free oil at the surface and consequent tuning of required hydrophobicity. This ...