Publicaties
Proteomic comparison between non-purified cerebrospinal fluid and cerebrospinal fluid-derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia Universiteit Gent Universiteit Antwerpen Vlaams Instituut voor Biotechnologie
The role of CSF biomarkers in the diagnostic work-up of mixed vascular-degenerative dementia Vrije Universiteit Brussel Universiteit Antwerpen
Low average specificity levels of 48% for clinical diagnosis of possible Alzheimer's disease (AD) reflect the overlap of clinical profiles between AD and non-AD dementias. Should diagnostic errors occur, they most likely involve one of the other primary dementias, mixed pathologies that include a vascular component, or uncertainties that are associated with early diagnosis. Vascular dementia (VaD) is overdiagnosed when a routine brain MRI or ...
The involvement of people with dementia in the design process KU Leuven
Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration Universiteit Antwerpen
Advance Care Planning in young-onset dementia Vrije Universiteit Brussel
Advance care planning (ACP) is considered as an essential element of high quality and ethically sound long-term care after a diagnosis of dementia. ACP is a process of communication between patients, family caregivers and professional caregivers in which the patient's preferences regarding (future) care are explored, including end-of-life care. The overarching goal of ACP is to increase the chance that individuals will ...
Defining the content of a website on advance care planning in dementia Vrije Universiteit Brussel KU Leuven
BACKGROUND: Advance care planning (ACP) is a process that enables individuals to define goals and preferences for their future care. It is particularly relevant for people with dementia and their family. Interactive tools, such as websites, that encourage reflection, communication and/or documentation, may support this group in the ACP process. However, considering the specific needs of people with dementia, it is important to develop adapted ...
Gait phenotype from mild cognitive impairment to moderate dementia Universiteit Antwerpen
Diagnostic Accuracy of Cerebrospinal Fluid Amyloid-β Isoforms for Early and Differential Dementia Diagnosis Vrije Universiteit Brussel Universiteit Antwerpen
BACKGROUND: Overlapping cerebrospinal fluid biomarkers (CSF) levels between Alzheimer's disease (AD) and non-AD patients decrease differential diagnostic accuracy of the AD core CSF biomarkers. Amyloid-β (Aβ) isoforms might improve the AD versus non-AD differential diagnosis.
OBJECTIVE: To determine the added diagnostic value of Aβ isoforms, Aβ(1-37), Aβ(1-38), and Aβ(1-40), as compared to the AD CSF biomarkers Aβ(1-42), T-tau, and ...