Nieuwe diagnostische en therapeutische benadering van inflammatoire darmaandoeningen op basis van functionele karakterisering van patiënten: de CrUCCial-index KU Leuven
The clinical phenotype and the outcome of Crohn's disease (CD) and ulcerative colitis (UC), the opposite ends of chronic inflammatory bowel diseases (IBD), are heterogeneous and represent the result of a complex interplay of the gut microbiome with the immune system in genetically predisposed individuals. Disease management is much less heterogeneous as all patients are treated using non-specific anti-inflammatory agents, and only 30-50% ...