High-fat nutrition reduces hepatic damage following exposure to bacterial DNA and hemorrhagic shock Universiteit Gent
Background/Aims: Bacterial infection combined with hypotension results in exacerbation of the inflammatory response with release of interferon (IFN) gamma. This excessive inflammation may lead to development of hepatic damage and liver failure. This study investigates the effect of dietary lipids on release of IFN-gamma and development of hepatic damage following exposure to synthetic bacterial DNA (CpG-ODN) and hemorrhagic shock.Methods: Rats ...