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A review on co-metabolic degradation of organic micropollutants during anaerobic digestion: Linkages between functional groups and digestion stages KU Leuven

Ilse Smets, Lise Appels
The emerging presence of organic micropollutants (OMPs) in water bodies produced by human activities is a source of growing concern due to their environmental and health issues. Biodegradation is a widely employed treatment method for OMPs in wastewater owing to its high efficiency and low operational cost. Compared to aerobic degradation, anaerobic degradation has numerous advantages, including energy efficiency and superior performance for ...

Ingestion of Casein in a Milk Matrix Modulates Dietary Protein Digestion and Absorption Kinetics but Does Not Modulate Postprandial Muscle Protein Synthesis in Older Men Vrije Universiteit Brussel

Tyler A Churchward-Venne, Armand M A Linkens, Henrike M Hamer, Janneau van Kranenburg, Luc Van Loon

BACKGROUND: The slow digestion and amino acid absorption kinetics of isolated micellar casein have been held responsible for its relatively lower postprandial muscle protein synthetic response compared with rapidly digested proteins such as isolated whey. However, casein is normally consumed within a milk matrix. We hypothesized that protein digestion and absorption kinetics and the subsequent muscle protein synthetic response after micellar ...

Steering digestion of lentil-based foods through structure engineering and advancing in vitro digestion methodologies KU Leuven

Dorine Duijsens
A more extensive incorporation of pulses within our diets has been proposed to feed the rising world population healthily and sustainably. Despite their potential, pulse consumption remains low in most western countries. It could be increased by the development of a wide range of convenient pulse-based products allowing consumers to improve the nutritional value of their diets without drastically changing eating habits. Within pulses, ...

Strategic choices for in vitro food digestion methodologies enabling food digestion design KU Leuven

Dorine Duijsens, Sarah Verkempinck, Marc Hendrickx, Ann Van Loey, Tara Grauwet
Background: In the past decades, the great interest in food digestion research led to a wide array of in vitro digestion (IVD) methods. Each of these methods have the potential of providing specific valuable scientific in- sights in digestion mechanisms and the rational structural design of foods. Scope and approach: This review paper outlines important transitions in recent IVD research and formulates important considerations relevant for the ...

In vitro protein and starch digestion kinetics of individual chickpea cells: from static to more complex in vitro digestion approaches KU Leuven

Daphne Michels, Dorine Duijsens, Marc Hendrickx, Ann Van Loey, Tara Grauwet
Attention has been given to more (semi-)dynamic in vitro digestion approaches ascertaining the consequences of dynamic in vivo aspects on in vitro digestion kinetics. As these often come with time and economical constraints, evaluating the consequence of stepwise increasing the complexity of static in vitro approaches using easy-to-handle digestion set-ups has been the center of our interest. Starting from the INFOGEST static in vitro protocol, ...

From static to semi-dynamic in vitro digestion conditions relevant for the older population: starch and protein digestion of cooked lentils KU Leuven

Dorine Duijsens, Sarah Verkempinck, Marc Hendrickx, Tara Grauwet
In the context of adequately feeding the rising older population, lentils have an important potential as sources of (plant-based) protein as well as slowly digestible bio-encapsulated starch and fibre. This study evaluated in vitro digestion of protein and starch in lentils under conditions representing the gastrointestinal tract of older adults. Both static and semi-dynamic simulations were applied to analyze the effect of specific ...

Importance of adapted digestion conditions to simulate in vitro lipid digestion of broilers in different life stages KU Leuven

Daphne Michels, Sarah Verkempinck, Marc Hendrickx, Tara Grauwet
In vitro digestion studies demonstrate large potential to gain more and quicker insights into the underlying mechanisms of feed additives, allowing the optimization of feed design. Unfortunately, current in vitro digestion models relevant for broiler chickens lack sufficient description in terms of protocols and standardisation used. Furthermore, no distinction is made between the different life phases of these animals (starter, grower, and ...

From single to multiresponse modelling of food digestion kinetics: The case of lipid digestion KU Leuven

Sarah Verkempinck, Marcos Ricardo Infantes Garcia, Marc Hendrickx, Tara Grauwet
This work presents that lipid digestion kinetics of oil-in-water emulsions can be described by a mechanism-based multiresponse model. The modelling approach proposed takes into account multiple interlinked responses of in vitro lipolysis. Different reaction schemes are proposed and iteratively adapted for one dataset. Based on model discrimination, the model that best described the experimental data was selected. This selected multiresponse ...