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Activity of Extracts and Naphthylisoquinoline Alkaloids From Triphyophyllum-peltatum, Ancistrocladus-abbreviatus and A-barteri Against Plasmodium-falciparum In-vitro Instituut voor Tropische Geneeskunde
In vitro inhibition of liver forms of the rodent malaria parasite Plasmodium berghei by naphthylisoquinoline alkaloids--structure-activity relationships of dioncophyllines A and C and ancistrocladine Instituut voor Tropische Geneeskunde
Naphthylisoquinoline alkaloids are derived from Dioncophyllaceae and Ancistrocladaceae species and comprise a new class of promising antimalarials with a demonstrated potential against asexual erythrocytic Plasmodium falciparum and P. berghei stages in vitro. We report herein the pronounced activity of pure naphthylisoquinoline alkaloids against exoerythrocytic malaria parasites. P. berghei-infected human hepatoma cells (Hep G2) were incubated ...