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Epigenetics in toxicology: the implications of epigenetic alterations driven by external exposures for human health Vrije Universiteit Brussel
The prospect that non-genotoxic environmental exposures of physical, chemical or social nature act on epigenetic mechanisms opens a new emerging field in toxicology. Epigenetics refers to the stable changes in gene expression programming that could alter the phenotype in absence of a change in DNA sequence. Epigenetic modifications, which include amongst others DNA methylation, covalent modifications of histone tails, and regulation by ...
Comprehensive histone epigenetics : a mass spectrometry based screening assay to measure epigenetic toxicity Universiteit Gent
Evidence of the involvement of epigenetics in pathologies such as cancer, diabetes, and neurodegeneration has increased global interest in epigenetic modifications. For nearly thirty years, it has been known that cancer cells exhibit abnormal DNA methylation patterns. In contrast, the large-scale analysis of histone post-translational modifications (hPTMs) has lagged behind because classically, histone modification analysis has relied on site ...
Epigenetics in aquaculture : the last frontier Universiteit Gent
Synthesizing the role of epigenetics in the response and adaptation of species to climate change in freshwater ecosystems Universiteit Gent
Genetics and epigenetics in clinical veterinary medicine : new approaches to deal with problems related to diagnostics and screening Universiteit Gent
Epigenetics, pregnancy and autoimmune rheumatic diseases Universiteit Gent
Linking Lifestyle Factors to Complex Pain States: 3 Reasons Why Understanding Epigenetics May Improve the Delivery of Patient-Centered Care Vrije Universiteit Brussel KU Leuven
Air Pollution-Induced Placental Alterations: An Interplay of Oxidative Stress, Epigenetics, and the Aging Phenotype? Universiteit Hasselt KU Leuven
According to the “Developmental Origins of Health and Disease” (DOHaD) concept, the early-life environment is a critical period for fetal programming. Given the epidemiological evidence that air pollution exposure during pregnancy adversely affects newborn outcomes such as birth weight and preterm birth, there is a need to pay attention to underlying modes of action to better understand not only these air pollution-induced early health effects ...