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ACE Ins/Del genetic polymorphism and epidemiological findings in COVID-19 Universiteit Gent

Joris Delanghe, Marijn Speeckaert, Marc De Buyzere
Prevalence/mortality of COVID-19 infection may be attributed to many variables. We have constructed a database of a single continuous geographical zone to neutralize as much as possible the confounders. The majority of the variance in COVID-19 prevalence / mortality cannot be explained by the ACE D/I polymorphism alone. Other variables have contributed to an important variation in the statistics. A comparison with the European/North ...

First survey on canine leishmaniasis in a non classical area of the disease in Spain (Lleida, Catalonia) based on a veterinary questionnaire and a cross-sectional study Instituut voor Tropische Geneeskunde

C. Ballart, M.M. Alcover, Albert Picado De Puig, J. Nieto, S. Castillejo, M. Portús, M. Gállego
The Spanish distribution of canine leishmaniasis (CanL) is heterogeneous and very few data are available for the north of the country, including the province of Lleida (Catalonia, Spain). This work describes the results obtained from a questionnaire sent to veterinarians throughout the province of Lleida. The majority of veterinarians (25/32, 78.1%) believed CanL cases were increasing and that the dogs had been infected locally (30/32, 93.8%). ...

Interruption or deferral of antiretroviral therapy reduces markers of bone turnover compared with continuous therapy: The SMART Body Composition substudy Instituut voor Tropische Geneeskunde

J. Hoy, B. Grund, M. Roediger, K.E. Ensrud, I. Brar, Robert Colebunders, N. De Castro, M. Johnson, A. Sharma, A. Carr, et al.
Bone mineral density (BMD) declines significantly in HIV patients on antiretroviral therapy (ART). We compared the effects of intermittent versus continuous ART on markers of bone turnover in the Body Composition substudy of the Strategies for Management of AntiRetroviral Therapy (SMART) trial and determined whether early changes in markers predicted subsequent change in BMD. For 202 participants (median age 44 years, 17% female, 74% on ART) ...

How do primary health care teams learn to integrate intimate partner violence (IPV) management? A realist evaluation protocol Instituut voor Tropische Geneeskunde

I. Goicolea, C. Vives-Cases, M. San Sebastian, Bruno Marchal, Guy Kegels, A.K. Hurtig
BACKGROUND: Despite the existence of ample literature dealing, on the one hand, with the integration of innovations within health systems and team learning, and, on the other hand, with different aspects of the detection and management of intimate partner violence (IPV) within healthcare facilities, research that explores how health innovations that go beyond biomedical issues-such as IPV management-get integrated into health systems, and that ...

Application of molecular techniques in the study of natural infection of Leishmania infantum vectors and utility of sandfly blood meal digestion for epidemiological surveys of leishmaniasis Instituut voor Tropische Geneeskunde

M.M. Alcover, M. Gramiccia, T. Di Muccio, C. Ballart, S. Castillejo, Albert Picado De Puig, M. Portús, M. Gállego
Epidemiological studies on the distribution of leishmaniasis caused by Leishmania infantum Nicolle, 1908 (Kinetoplastida: Trypanosomatidae) have been based principally on serological surveys of the canine reservoir. This methodology is useful due to the facility of sampling, the rapidity in obtaining results, its consistency and because it allows the detection of heterogeneous foci of canine leishmaniasis (CanL) even in small areas. Other ...

Comparison of bovine cysticercosis prevalence detected by antigen ELISA and visual inspection in the North East of Spain Instituut voor Tropische Geneeskunde

A. Allepuz, Sarah Gabriël, Pierre Dorny, S. Napp, Famke Jansen, M.J. Vilar, L. Vives, L. Picart, A. Ortuño, J. Gutiérrez, et al.
A cross-sectional serological study on cattle less than 2years old, using an antigen ELISA for the detection of bovine cysticercosis was carried out between November 2009 and February 2010 in 10 slaughterhouses from the Catalonia region (North-Eastern Spain). Circulating antigen was detected in 23 of 2073 animals, i.e. a sero-prevalence of 1.11% (CI95%: 0.76-1.75%). The determined sero-prevalence was about 50 times higher than the prevalence ...