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Promoting research integrity in funding: Co-creating guidelines for research funding organizations Universiteit Hasselt KU Leuven

Noemie AUBERT BONN
Research Funding Organizations (RFOs) play an important role in promoting research integrity (RI). Not only do they allocate resources to research institutions and researchers, but they also set and monitor research standards in their funded projects. In spite of their crucial role, there is a paucity of guidance on how RFOs can promote research integrity. As part of the EU-Funded SOPs4RI project, we aimed to address this gap by co-creating ...

Does industry funding and study location impact findings from randomized controlled trials of spinal cord stimulation? Vrije Universiteit Brussel

Sam Eldabe, Sarah Nevitt, Sue Copley, Michelle Maden, Lisa Goudman, Salim M Hayek, Nagy Mekhail, Maarten Moens, Phillipe Rigoard, Rui Duarte, et al.

BACKGROUND/IMPORTANCE: Concerns have been raised that effects observed in studies of spinal cord stimulation (SCS) funded by industry have not been replicated in non-industry-funded studies and that findings may differ based on geographical location where the study was conducted.

OBJECTIVE: To investigate the impact of industry funding and geographical location on pain intensity, function, health-related quality of life and adverse ...

Bank funding, securitization, and loan terms: Evidence from foreign currency lending KU Leuven

Steven Ongena
© 2014 The Ohio State University. We examine how bank funding structure and securitization activities affect the currency denomination of business loans. We analyze a unique data set that includes information on the requested and granted loan currency for 99,490 loans granted to 57,464 firms by a Bulgarian bank. Our findings document that foreign currency lending is at least partially driven by bank eagerness to match the currency structure of ...

Finding the Key: Binding of Metal-Oxo Clusters to the Enzyme Active Site Enabled by "Click" (Bio)Conjugation KU Leuven

Givi Kalandia, Kilian Declerck, Mhamad Aly Moussawi, Tatjana Vogt
Molecular metal-oxo nanoclusters with tunable redox and structural properties have emerged as powerful bio-inorganic tools in catalysis, protein crystallization, and therapeutic applications. Despite their potential, interactions between discrete clusters and proteins are predominantly driven by nonspecific intermolecular interactions, which limit precise control over binding sites and functional outcomes. In this work, we introduce a new ...

Finding the meaning in meaning maps: Quantifying the roles of semantic and non-semantic scene information in guiding visual attention KU Leuven

Maarten Leemans, Johan Wagemans
In real-world vision, people prioritise the most informative scene regions via eye-movements. According to the cognitive guidance theory of visual attention, viewers allocate visual attention to those parts of the scene that are expected to be the most informative. The expected information of a scene region is coded in the semantic distribution of that scene. Meaning maps have been proposed to capture the spatial distribution of local scene ...

New findings on the contribution of Mg-Al-NO3 layered double hydroxides to the hydration and chloride binding capacity of cement pastes Universiteit Gent KU Leuven

Mohammadali Yazdi, Elke Gruyaert, Kim Van Tittelboom, Nele De Belie
The impact of the addition of layered double hydroxides (LDHs) on binding of chloride ions was studied by pore expression experiments. A Mg-Al-NO3 type of LDHs was added to paste samples blended with 3 % NaCl in different proportions (4 % and 10 % by mass of the binder). In addition, the influence of LDHs on the hydration process, morphology and porosity of samples containing Portland cement, calcium sulphoaluminate cement and silica fume was ...

Energetic basis of uncoupling folding from binding for an intrinsically disordered protein Vrije Universiteit Brussel

Igor Drobnak, Natalie De Jonge, Sarah Haesaerts, G. Vesnaver, Remy Loris, Jurij Lah
Intrinsically disordered proteins (IDPs) are proteins that lack a unique three-dimensional structure in their native state. Many have, however, been found to fold into a defined structure when interacting with specific binding partners. The energetic implications of such behavior have been widely discussed, yet experimental thermodynamic data is scarce. We present here a thorough thermodynamic and structural study of the binding of an IDP ...

Feeding intolerance scoring system in very preterm and very low birth weight infants using clinical and ultrasound findings Vrije Universiteit Brussel

Evita Karianni Bermanshah Ifran, Badriul Hegar, Rinawati Rohsiswatmo, Wresti Indriatmi, Tetty Yuniarti, Najib Advani, Dewi Irawati Soeria Santoso, Marshita Masui, Hardya Gustada Hikmahrachim, Koen Huysentruyt, et al.

Very preterm infants are at a high risk of developing feeding intolerance; however, there are no widely accepted definitions of feeding intolerance. This study aimed to develop a scoring system for feeding intolerance in very preterm infants by combining clinical symptoms and ultrasonography (US) findings. This prospective cohort study included very preterm and/or very low birth weight infants. We defined feeding intolerance as the inability ...