Publicaties
Complete molecular genome analyses of equine rotavirus A strains from different continents reveal several novel genotypes and a largely conserved genotype constellation KU Leuven
Complete molecular genome analyses of equine rotavirus strains from different continents reveal several new genotypes and a largely conserved genotype constellation KU Leuven
Single-step real-time PCR to quantify hepatitis B virus and distinguish genotype D from non-D genotypes KU Leuven
ResFinder 4.0 for predictions of phenotypes from genotypes Instituut voor Tropische Geneeskunde Universiteit Antwerpen
Objectives: WGS-based antimicrobial susceptibility testing (AST) is as reliable as phenotypic AST for several antimicrobial/bacterial species combinations. However, routine use of WGS-based AST is hindered by the need for bioinformatics skills and knowledge of antimicrobial resistance (AMR) determinants to operate the vast majority of tools developed to date. By leveraging on ResFinder and PointFinder, two freely accessible tools that can ...
DNA repair enzyme genotypes and their toxicologically relevant phenotypes Vrije Universiteit Brussel
(hOGG1) Ser326Cys variant genotype and increased risk of various types of cancer; (b) the X-ray repair cross-complementing group 1 (XRCC1) Arg194Trp variant genotype ...
Phenotypes and genotypes in non-consanguineous and consanguineous primary microcephaly Universiteit Antwerpen KU Leuven Vrije Universiteit Brussel Universiteit Gent
Phenotypes and genotypes of Chinese adult patients with systemic autoinflammatory diseases KU Leuven
Analysis of MUTYH Genotypes and Colorectal Phenotypes in Patients With MUTYH-Associated Polyposis Vrije Universiteit Brussel
Background & Aims: Biallelic mutations in the base excision DNA repair gene MUTYH lead to MUTYH-associated polyposis (MAP) and predisposition to colorectal cancer (CRC). Functional studies have demonstrated significant differences in base recognition and glycosylase activity between various MUTYH mutations, notably for the 2 mutations most frequently reported in MAP patients: Y179C and G396D (previously annotated as Y165C and G382D). Our ...