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Afatinib for EGFR, HER2 or HER3 mutated solid tumors: A phase II Belgian precision study Universiteit Hasselt
Background: The Belgian Precision initiative aims to implement tumor-agnostic NGS in advanced cancer patients (pts) and enhance access to genotype-matching drugs. The current study aimed to investigate the efficacy of afatinib in advanced pre-treated solid cancers with an EGFR (excluding non-small cell lung cancer (NSCLC)), HER2 or HER3 mutation.
Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines Universiteit Antwerpen
The epidermal growth factor receptor (EGFR, HER1) is a therapeutic target in head and neck squamous cell carcinoma (HNSCC). After initial promising results with EGFR-targeted therapies such as cetuximab, therapeutic resistance has become a major clinical problem, and new treatment options are therefore necessary. Moreover, the relationship between HER receptors, anti-EGFR therapies, and the human papillomavirus (HPV) status in HNSCC is not fully ...
Hart boven Hard op een kruispunt Universiteit Gent
Hart boven Hard nam in september 2014 een vliegende start en ontpopte zich al gauw tot de motor voor een hernieuwde politisering van het middenveld. De beweging bestaat ondertussen meer dan twee en half jaar. Op 7 mei staat alweer een volgende Grote Parade gepland. Vandaag staat Hart boven Hard echter op een kruispunt en krijgt de beweging met interne spanningsvelden te maken, die het zal moeten overwinnen om een gamechanger te zijn.
Hard boven Hart op een kruispunt Universiteit Antwerpen
Hart boven Hard Universiteit Antwerpen
Hart boven hard KU Leuven
“Trust us: Bootcamp Pilates does not sound half as hard as it is, but it works”: The credibility of women’s magazines Vrije Universiteit Brussel
In this chapter, I will consider the communication of women's magazines with their readers to be a special kind of organizational communication. The way this communication is established projects interpersonal relations, but women's magazines can be considered to be organizations in that they are structured units which pursue collective goals. What is special is that, being mass media, their main communication (i.e. with their readers/buyers) is ...
rsHRF: A toolbox for resting-state HRF estimation and deconvolution KU Leuven
The hemodynamic response function (HRF) greatly influences the intra- and inter-subject variability of brain activation and connectivity, and might confound the estimation of temporal precedence in connectivity analyses, making its estimation necessary for a correct interpretation of neuroimaging studies. Additionally, the HRF shape itself is a useful local measure. However, most algorithms for HRF estimation are specific for task-related fMRI ...