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Disease-related malnutrition with inflammation and cachexia Vrije Universiteit Brussel

Maurizio Muscaritoli, Giovanni Imbimbo, Harriëtte Jager-Wittenaar, Tommy Cederholm, Elisabet Rothenberg, Filippo Giorgio Di Girolamo, Maria Ida Amabile, Martine Sealy, Stéphane M. Schneider

In 2010, the definition of cachexia was jointly developed by the European Society for Clinical Nutrition and Metabolism (ESPEN) Special Interest Groups (SIG) "Cachexia-anorexia in chronic wasting diseases" and "Nutrition in geriatrics". Cachexia was considered as a synonym of disease-related malnutrition (DRM) with inflammation by the ESPEN guidelines on definitions and terminology of clinical nutrition. Starting from these concepts and ...

Micronuclei, inflammation and auto-immune disease Vrije Universiteit Brussel

Micheline Volders, Claudia Bolognesi, Marcello Ceppi, Marco Bruzzone, Michael Fenech

Auto-immune diseases (AUD) are characterized by an immune response to antigenic components of the host itself. The etiology of AUD is not well understood. The available evidence points to an interaction between genetic, epigenetic, environmental, infectious and life-style factors. AUD are more prevalent in women than in men; sex hormones play a crucial role in this sex bias. Micronuclei (MN) emerged as a new player in the induction of AUD, ...