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Intestinal helminthic infections: a narrative review to guide the hepatogastroenterologist Instituut voor Tropische Geneeskunde Vrije Universiteit Brussel

M Vanhooren, Anke Stoefs, Steven Van Den Broucke, Marjan Van Esbroeck, T Demuyser, S Kindt

Intestinal helminthic infections are not uncommon in Western Europe, mainly due to modern travel, emigration and globalization. Moreover, some helminthic infections are endemic in Western Europe and are part of the everyday clinical practice. The hepatogastroenterologist should therefore recognize and manage these patients or at least refer them to appropriate reference centers. Signs and symptoms are often unspecific or even absent. ...

Diagnosis of neglected tropical diseases among patients with persistent digestive disorders (diarrhoea and/or abdominal pain >= 14 days): Pierrea multi-country, prospective, non-experimental case-control study KU Leuven

Jan Jacobs, Raffaella Ravinetto
BACKGROUND: Diarrhoea still accounts for considerable mortality and morbidity worldwide. The highest burden is concentrated in tropical areas where populations lack access to clean water, adequate sanitation and hygiene. In contrast to acute diarrhoea (<14 days), the spectrum of pathogens that may give rise to persistent diarrhoea (≥14 days) and persistent abdominal pain is poorly understood. It is conceivable that pathogens causing neglected ...

Diagnosis of neglected tropical diseases among patients with persistent digestive disorders (diarrhoea and/or abdominal pain ≥14 days) Instituut voor Tropische Geneeskunde

Katja Polman, Sören L Becker, Emilie Alirol, Nisha K Bhatta, Narayan R Bhattarai, Emmanuel Bottieau, Martin W Bratschi, Sakib Burza, Jean T Coulibaly, Mama N Doumbia, et al.

BACKGROUND: Diarrhoea still accounts for considerable mortality and morbidity worldwide. The highest burden is concentrated in tropical areas where populations lack access to clean water, adequate sanitation and hygiene. In contrast to acute diarrhoea (<14 days), the spectrum of pathogens that may give rise to persistent diarrhoea (≥14 days) and persistent abdominal pain is poorly understood. It is conceivable that pathogens causing ...

Schistosomiasis in travellers and migrants Instituut voor Tropische Geneeskunde

Joannes Clerinx, Alfons Van Gompel
Schistosomiasis is a tropical parasitic disease caused by blood-dwelling fluke worms of the genus Schistosoma whose infective stages, the cercariae, are amplified through mollusks acting as intermediate hosts. People are infected when exposed to fresh water containing cercariae that penetrate the skin. There are however considerable differences in intensity of infection and morbidity, depending on the pattern of exposure and the infective ...

Where have all the diagnostic morphological parasitologists gone? Instituut voor Tropische Geneeskunde

Richard S Bradbury, Sarah G H Sapp, Idzi Potters, Blaine A Mathison, John A Frean, Abhishek Mewara, Harsha Sheorey, Francesca Tamarozzi, Marc Roger Couturier, Peter Chiodini, et al.

Advances in laboratory techniques have revolutionized parasitology diagnostics over the past several decades. Widespread implementation of rapid antigen detection tests has greatly expanded access to tests for global parasitic threats such as malaria, while next-generation amplification and sequencing methods allow for sensitive and specific detection of human and animal parasites in complex specimen matrices. Recently, the introduction of ...

Advances in the diagnosis of Ascaris suum infections in pigs and their possible applications in humans Universiteit Gent

Johnny Vlaminck, Bruno Levecke, Jozef Vercruysse, Peter Geldhof
Ascariasis is one of the most common parasitic diseases in both humans and pigs. It has been shown to cause growth deficits in both species and to impair cognitive development in children. Notwithstanding its substantial impact on pig economy and public health, diagnosis of ascariasis has mostly relied on the detection of eggs in stool and further development of novel, more sensitive methods has been limited or non-existent. Here, we discuss the ...

Human fascioliasis in Africa : a systematic review Universiteit Gent Instituut voor Tropische Geneeskunde

Veronique Dermauw, Joan Muchai, Yara Al Kappany, Ana Lucia Fajardo Castaneda, Pierre Dorny
Fascioliasis is a globally distributed, parasitic zoonosis, caused by Fasciola hepatica and F. gigantica. A comprehensive overview of the epidemiology of human fascioliasis in Africa is missing up to now. Therefore, our objective was to conduct a systematic review aiming to summarize recent knowledge on the distribution, prevalence, and risk factors of human fascioliasis in Africa. A key word search was performed in PubMed, Web of Science and ...

Hepatic schistosomiasis with massive splenomegaly: a case report and literature review Universiteit Hasselt

L. Thijs, Peter MESSIAEN, Jeroen VAN DER HILST, V. Madoe, C. Melis, P. Van Eyken, Ignace Vanmoerkerke, F. Janssens
Schistosomiasis is a parasitic disease caused by Schistosoma species. Intestinal and hepatic schistosomiases are the most common forms of chronic disease. We describe a case of a 26-year old patient from Eritrea who was referred to our hospital with abdominal pain and diarrhea. The diagnosis of hepatosplenic schistosomiasis was made by liver biopsy and the patient was treated with praziquantel. Hepatic schistosomiasis is characterised by ...