MDM4 proteine, een veelbelovend doelwit voor kankertherapie KU Leuven
Cutaneous melanoma arises from uncontrolled growth of melanocytes in the basal layer of the skin. It is a very aggressive disease and its incidence has been rising faster than any other cancer type since the mid 1950’s. Once the cancer has metastasized to other organs, it becomes very difficult to manage. Recently, the melanoma field was revolutionized by the upcoming of MAPK-based targeted therapeutics and immunotherapy. In spite of initial ...