Publicaties

Purpose: To evaluate the long term results and the characteristics of patients treated with high dose chemotherapy (HDCT) for an advanced germ cell tumour at Ghent University Hospital from 1996 to 2010. Materials and Methods: A retrospective analysis of patients treated with HDCT for germ cell tumours was performed. Data about stage at diagnosis, different prognostic scoring systems, timing of HDCT, response to HDCT and relapse-free period were ...

© 2018 The British Psychological Society Purpose: Children sometimes receive misinformation after being formally interviewed about their experiences in cases of suspected abuse. Following decades of research, many guidelines have been produced for interviewers so they can obtain reliable statements in children, like, for example, the NICHD protocol. One might expect that completing an early interview following research-based guidelines might ...

Aim: Evaluate long-term real-world treatment patterns and associated effectiveness and safety outcomes in patients with diabetic macular edema (DME) treated >= 36 months with 0.5mg ranibizumab. Methods: Open-label observational effectiveness study in 9 Belgian clinics. Included were primary treated eyes of 55 DME patients between August 2014 and March 2015 and followed for 3.5 +/- 1.8 years. Eyes were 21.8% treatment (TX)-naive, 9.1% ...

BackgroundAGI-101H is an allogeneic gene modified whole cell therapeutic melanoma vaccine, evaluated in over 400 melanoma patients in the adjuvant and therapeutic settings. We present updated long-term survival results from two single-arm, phase II adjuvant trials (Trial 3 and Trial 5) with the focus on treatment beyond recurrence of the disease.MethodsPatients with resected high-risk melanoma (stage IIIB-IV) were enrolled to Trial 3 (n=99) and ...

Repetition suppression (RS) reflects a neural attenuation during repeated stimulation. We used fMRI and the subsequent memory paradigm to test the predictive coding hypothesis for RS during visual memory processing by investigating the interaction between RS and differences due to memory in category-selective cortex (FFA, pSTS, PPA, and RSC). Fifty-six participants encoded face and house stimuli twice, followed by an immediate and delayed ...

Phosphorus (P) is an essential nutrient for all living organisms. P is present in every living cell, and no other element can replace it in its vital role in several physiological and biochemical processes. However, its supply in the earth’s crust is limited. P is of most concern because of the rate of exploitation of this non-renewable resource to meet current demand. Globally, recycling processes gain in interest to reduce the required amount ...

This doctoral thesis examines the provision of physical healthcare for individuals with severe mental illness (SMI) within Belgian mental health outreach teams. Given that people with SMI face significantly higher rates of physical comorbidities and reduced life expectancy, the research addresses the urgent need to bridge the gap between mental and physical health services. The study explores both the structure and effectiveness of long-term ...

This paper argues that serious games offer opportunities for civic engagement. This engagement is necessary for a good functioning democracy and as such context in which civic engagement flourishes must be nurtured. Games arguably offer such a context by facilitating a playful way of engaging with complex issues, such as poverty. Furthermore, games can provide a context that allows different angles for different players in terms of the same ...

STEM presents a challenge to education at large. The enrollment numbers in higher education STEM tracks are ever-decreasing numbers all around the globe. More so, young people’s interest in and attitudes towards STEM seem to be free falling. Educational interventions that can help boost the attractiveness of STEM are therefore needed, and diverse such interventions are implemented worldwide. We present a longitudinal impact study of a STEM ...

An internationally accepted method for the safe management of high-level radioactive waste is deep geological disposal. In Belgium, two clay formations are considered suitable for this purpose: the Boom Clay and the Ypres Clay. It is possible to create an underground network of concrete shafts in these disposal formations. The radioactive waste will ultimately be stored in these shafts, surrounded by multiple barriers. The waste is typically ...