NOVEL USE AND METHOD COMPRISING IL-2 AND A TISSUE- OR ORGAN-SPECIFIC TARGETING MOIETY Vlaams Instituut voor Biotechnologie
The invention relates to a pharmaceutical composition for use in a method of treating and/or preventing amyotrophic lateral sclerosis (ALS), said composition comprising IL-2 and a targeting moiety specific for a tissue or organ of a subject, such as the central nervous system and the brain. Also provided are methods for treating and/or preventing ALS, said methods comprising expanding a population of regulatory T cells and/or administration of a pharmaceutical composition as defined herein.