The complete in vitro Plasmodium vivax cycle as a first step for understanding its biology and identifying new therapeutic targets. Instituut voor Tropische Geneeskunde
P. vivax represents a huge burden on the
health, longevity, and socio-economic development of large sections of the
human population. Despite its importance, research on P. vivax lags behind that on P.
falciparum, seriously compromising the development of adequate tools for
its control. Besides less resources available (as compared to P. falciparum), the failure to achieve
continuous culture of P. ...
Utilization of molecular resistance test results as tools to support public health efforts for improved control of rifampicin resistant tuberculosis Instituut voor Tropische Geneeskunde
African trypanosome transmission: unraveling the molecular 'tripartite' between a protozoan parasite, a symbiotic bacterium and the tsetse fly innate immunity Instituut voor Tropische Geneeskunde
This study focuses on understanding molecular pathways involved in developmental and reproductive toxicity and how it might affect the phenotype of an organism. Understanding conserved molecular pathways in humans and alternative test species can lead to the development of better testing methodologies, that might reduce biological testing on animals.
'Molecular Imaging' onmoet 'Imaging Molecules' Universiteit Antwerpen
Simplified rapid molecular diagnosis and characterisation of Leishmaniasis and Human African Trypanosomiasis Instituut voor Tropische Geneeskunde
To generate new knowledge and technologies for improved diagnosis and control of human African trypanosomiasis and leishmaniasis.
To develop and validate low-tech molecular tests for laboratory diagnosis and (sub-)species differentiation.To develop and validate a sensitive point-of-care test for differential molecular diagnosis based on ribosomal RNA (rRNA) detection.To strengthen research ...
A multi-disciplinary international effort to identify clinical, molecular and social factors impacting cutaneous leishmaniasis Instituut voor Tropische Geneeskunde
in the Mediterranean basin and declared as emerging diseases in the EU due to climate change and population
displacement. The LeiSHield-MATI consortium will for the first time investigate in an integrative fashion the complex
parasite-vector-host interplay in cutaneous leishmaniasis affecting Morrocco, Algeria, Tunisia, ...