Publicaties

This article discusses the post-Nicene passio Chrysanthi et Dariae (BHL 1787-1787a-1788) and aims to demonstrate that this text gives evidence of more literary subtlety than the late antique passions usually get credit for. To underpin this claim, we analyze the characterization of the passion's protagonists Chrysanthus and Daria. The characterization reveals, we contend, how the passio takes different, ambiguous approaches to traditional gender ...

This dataset provides the latest characterization factors for ozone depletion based on the most recent ozone depletion potentials from the 2022 World Meteorological Organization (WMO) scientific assessment. These characterization factors can be used in life cycle assessment (LCA) to convert emissions of ozone-depleting substances to the common unit of the ozone depletion impact category, measured in kg CFC-11-eq. The dataset is formatted for ...

Chronic musculoskeletal pain and sleep problems/disorders exhibit a recognized bidirectional relationship; yet, systematic investigations of this claim, particularly in a prospective context, are lacking. This systematic review with meta-analysis aimed to synthesize the literature on the prospective associations between sleep problems/disorders and chronic musculoskeletal pain. A comprehensive search across 6 databases identified prospective ...

Patients presenting with or alerting emergency networks due to acute heart failure (AHF) form a diverse group with a plethora of symptoms, risks, comorbidities, and aetiologies. During AHF, there is an increased risk of destabilizing the functional substrate and modulatory adding to the risk of ventricular arrhythmias (VAs) already created by the structural substrate. New VAs during AHF have previously identified patients with higher ...

Methyl-CpG-binding protein 2 (MeCP2) is a ubiquitously expressed nuclear protein involved in transcriptional regulation and chromatin remodeling. MeCP2 exists in two isoforms, MeCP2 E1 and E2, which share the same functional domains. Loss-of-function mutations in the MeCP2 gene are the main cause of Rett syndrome (RTT). Previous studies identified a complex formation between MeCP2 and lens epithelium derived growth factor (LEDGF), a ...

Behavioural analysis has been attracting significant attention as a broad indicator of sub-lethal toxicity and has secured a place as an important subdiscipline in ecotoxicology. Among the most notable characteristics of behavioural research, compared to other established approaches in sub-lethal ecotoxicology (e.g. reproductive and developmental bioassays), are the wide range of study designs being used and the diversity of endpoints ...

IMPORTANCE: Cerebral small vessel disease (SVD) is associated with various cerebrovascular outcomes, but data on sex differences in SVD are scarce. OBJECTIVE: To investigate whether the frequency, severity, and distribution of cerebral microbleeds (CMB), other SVD markers on magnetic resonance imaging (MRI), and outcomes differ by sex. DESIGN, SETTING, AND PARTICIPANTS: This cohort study used pooled individual patient data from the Microbleeds ...

BACKGROUND AND OBJECTIVES: Acute ischemic stroke patients with a large vessel occlusion (LVO) who present to a primary stroke center (PSC) often require transfer to a comprehensive stroke center (CSC) for thrombectomy. Not much is known about specific characteristics at the PSC that are associated with infarct growth during transfer. Gaining more insight into these features could aid future trials with cytoprotective agents targeted at slowing ...